North Jeffrey P, Lo Justin, Landers Maeran
Department of Dermatology, Oregon Health & Science University, Portland, USA.
Cutis. 2012 Feb;89(2):81-3.
The poroid family of neoplasms includes hidroacanthoma simplex, eccrine poroma, dermal duct tumor, and poroid hidradenoma. These benign adnexal neoplasms are derived from the eccrine or apocrine sweat ducts or glands. Poroid neoplasms, including poromas, have been reported during pregnancy and have been hypothesized to be hormonally influenced. Poromatosis, the occurrence of multiple poromas, rarely has been reported in association with hidrotic ectodermal dysplasia, prior radiation therapy, and non-Hodgkin lymphoma occurring after chemotherapy. We report a case of eruptive poromatosis in pregnancy with 8 poromas occurring in the third trimester, further supporting the hypothesis of a hormonal association in the etiology of this neoplasm.
肿瘤性类孔状病变家族包括单纯性汗腺棘皮瘤、小汗腺汗孔瘤、皮肤导管瘤和类孔状汗腺腺瘤。这些良性附属器肿瘤起源于小汗腺或大汗腺导管或腺体。包括汗孔瘤在内的类孔状肿瘤在孕期已有报道，并被推测受激素影响。多发性汗孔瘤（即出现多个汗孔瘤）很少与汗管外胚层发育不良、既往放疗及化疗后发生的非霍奇金淋巴瘤相关。我们报告1例孕期爆发性多发性汗孔瘤病例，在孕晚期出现8个汗孔瘤，进一步支持该肿瘤病因中激素关联的假说。
