Neuroradiology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, 201133 Milan, Italy.
Neuroimaging Clin N Am. 2009 Nov;19(4):573-96. doi: 10.1016/j.nic.2009.08.010.
Functional magnetic resonance (fMR) imaging and diffusion MR tractography have emerged as valuable tools in the evaluation of verbal language in brain tumor patients, and have changed the way neurosurgeons look at patients with a mass in the dominant hemisphere. The techniques have obtained recognition as valuable presurgical clinical tools in the determination of hemispheric dominance and in the selection of candidates who may benefit from awake craniotomy. In the near future fMRI and diffusion MR Tractography may contribute to elucidate mechanisms of brain plasticity and may provide predictors of favorable postoperative clinical outcome. The functional anatomy of the language network and the role of fMR imaging and diffusion MR tractography in the evaluation of patients with a brain tumor are the focus of this article.
功能磁共振成像（fMRI）和弥散张量磁共振成像（DTI）已成为评估脑肿瘤患者语言功能的重要工具，改变了神经外科医生对优势半球占位患者的看法。这些技术已被公认为有价值的术前临床工具，可用于确定优势半球，并选择可能从清醒开颅术中获益的患者。在不久的将来，功能磁共振成像和弥散张量磁共振成像可能有助于阐明脑可塑性的机制，并为术后临床转归良好提供预测指标。本文聚焦于语言网络的功能解剖以及功能磁共振成像和弥散张量磁共振成像在脑肿瘤患者评估中的作用。
