Institut de Recherche Interdisciplinaire (IRI, USR 3078), Parc de la Haute Borne, Villeneuve d'Ascq, France.
Biosens Bioelectron. 2010 Jan 15;25(5):1199-203. doi: 10.1016/j.bios.2009.10.012. Epub 2009 Oct 29.
This paper describes a novel platform for preparing localized surface plasmon resonance (LSPR) sensing surfaces. It is based on the coating of gold nanostructures deposited on glass with an amorphous silicon-carbon alloy overcoating. The interest in coating the Au NSs with an amorphous silicon-carbon alloy resides in the possibility of incorporating carboxyl functions directly onto the surface via Si-C covalent bonds. This permits the use of hyrdosilylation reactions to modify the sensor surface. The use of this multilayer structure for the detection of hybridization events is discussed.
本文描述了一种用于制备局域表面等离子体共振（LSPR）传感表面的新型平台。它基于在玻璃上沉积的金纳米结构，再用非晶硅-碳合金进行覆盖。之所以对 Au NSs 进行非晶硅-碳合金覆盖感兴趣，是因为有可能通过 Si-C 共价键直接将羧基功能引入表面。这使得可以使用硅氢化反应来修饰传感器表面。讨论了这种多层结构在检测杂交事件中的应用。
