Department of Surgery, Kansai Medical University, Osaka, Japan.
Pancreas. 2010 Mar;39(2):165-70. doi: 10.1097/MPA.0b013e3181bd672c.
After standardization of the perioperative management of pancreaticoduodenectomy, we retrospectively compared results in nonstented pancreaticojejunostomy with external-stented pancreaticojejunostomy.
The study population included 129 consecutive patients who underwent pancreaticoduodenectomy between 2004 and 2008. The postoperative mortality and morbidity were compared between 51 patients with restrictive use of external stenting (group A) and 78 patients without external stenting (group B). The patient with a pancreatic duct of less than 3 mm in diameter was 31% in group A and 46% in group B.
There were no differences in postoperative morbidity and mortality between the 2 groups. Although the frequency of overall postoperative pancreatic fistula development was significantly higher in group B than in group A (44% vs 27%, P = 0.0004), there was no difference in grade B/C postoperative pancreatic fistula rate (group A: 5.9% vs group B: 14.1%). The length of in-hospital stay in group B was significantly shorter than group A (13 vs 24 days, P < 0.0001). There were no differences in postoperative morbidity and mortality between subgroups that were consisted of patients with small pancreatic duct diameter.
This retrospective single-center study showed that nonstented duct-to-mucosa anastomosis was a safe procedure and was associated with a shortened in-hospital stay.
在对胰十二指肠切除术围手术期处理进行标准化后,我们回顾性比较了非支架支撑胰肠吻合术与外支架支撑胰肠吻合术的结果。
本研究纳入了 2004 年至 2008 年间连续接受胰十二指肠切除术的 129 例患者。比较了限制性使用外支架(A 组)和不使用外支架(B 组)的 51 例患者和 78 例患者的术后死亡率和发病率。A 组中胰管直径小于 3mm 的患者占 31%,B 组中占 46%。
两组患者的术后发病率和死亡率无差异。尽管 B 组总的术后胰瘘发生率明显高于 A 组(44%比 27%,P=0.0004),但 B 组和 C 级术后胰瘘发生率(A 组:5.9%比 B 组:14.1%)无差异。B 组的住院时间明显短于 A 组(13 天比 24 天,P<0.0001)。在胰管直径较小的亚组中,两组患者的术后发病率和死亡率均无差异。
这项回顾性单中心研究表明,非支架支撑的胰管黏膜吻合术是一种安全的手术方法,可缩短住院时间。