Imaizumi Toshihide, Hatori Takashi, Tobita Kousuke, Fukuda Akira, Takasaki Ken, Makuuchi Hiroyasu
Department of Gastroenterological Surgery, Tokai University School of Medicine, Bohseidai, Isehara, 259-1193, Japan.
J Hepatobiliary Pancreat Surg. 2006;13(3):194-201. doi: 10.1007/s00534-005-1037-5.
There is a high risk of anastomotic leakage after pancreaticojejunostomy following pancreaticoduodenectomy in patients with a normal soft pancreas because of the high degree of exocrine function. Therefore, pancreaticojejunostomy is generally performed using a stenting tube (stented method). However, pancreaticojejunostomy with a certain duct-to-mucosa anastomosis does not always require a stenting tube, even in patients with a normal soft pancreas. Recently, we have performed pancreaticojejunostomy with duct-to-mucosa anastomosis without a stenting tube (nonstented method) and obtained good results.
The point of this technique is to maintain adequate patency of the anastomosis using a fine atraumatic needle and monofilament thread. The results of end-to-side pancreaticojejunostomy of the normal soft pancreas using the nonstented method (n = 123) were compared with those using the stented method (n = 45).
There were no differences in background characteristics between the groups, including age, gender, and disease. The mean times to complete pancreaticojejunostomy were around 30 min in the two groups and the rates of morbidity and leakage of pancreaticojejunostomy were 26.8% and 5.7% in the nonstented group and 22.2% and 6.7% in the stented group, respectively. These differences were not statistically significant. One patient in the stented group died of sepsis following leakage of pancreaticojejunostomy. There were also no significant differences in the mean time to initiation of solid food intake or postoperative hospital stay.
In conclusion, complete pancreaticojejunostomy using duct-to-mucosa anastomosis for a normal soft pancreas does not require a stenting tube. This nonstented method can be considered one of the basic procedures for pancreaticojejunostomy because of its safety and certainty.
在胰腺质地正常的患者中,胰十二指肠切除术后胰肠吻合口漏的风险较高,这是由于外分泌功能较强。因此,胰肠吻合术一般采用置管法(带支架法)。然而,即使在胰腺质地正常的患者中,采用特定的胰管-黏膜吻合方式的胰肠吻合术并不总是需要置管。最近,我们开展了不使用置管的胰管-黏膜吻合胰肠吻合术(无支架法)并取得了良好效果。
该技术的要点是使用精细无损伤针和单丝线保持吻合口的充分通畅。将采用无支架法(n = 123)对正常质地胰腺行端侧胰肠吻合术的结果与采用带支架法(n = 45)的结果进行比较。
两组患者的背景特征无差异,包括年龄、性别和疾病。两组完成胰肠吻合术的平均时间均约为30分钟,无支架组胰肠吻合术的发病率和漏出率分别为26.8%和5.7%,带支架组分别为22.2%和6.7%。这些差异无统计学意义。带支架组有1例患者因胰肠吻合口漏死于败血症。开始进食固体食物的平均时间或术后住院时间也无显著差异。
总之,对于正常质地胰腺采用胰管-黏膜吻合进行完全胰肠吻合术不需要置管。由于其安全性和确定性,这种无支架法可被视为胰肠吻合术的基本术式之一。