Department of Ophthalmology, National University Hospital, Singapore.
Singapore Med J. 2009 Nov;50(11):e371-3.
We report idiopathic hypertrophic pachymeningitis in a previously-healthy 34-year-old Filipino man, who presented with third and sixth cranial nerve palsies, headache, vomiting and left proptosis. Magnetic resonance imaging of the brain showed diffuse dural thickening and enhancement, with mild cerebrospinal fluid lymphocytosis and slight protein elevation. The patient was treated with anti-tuberculous medications and steroids, and made good recovery. We discuss the differential diagnoses and various diagnostic tests with respect to granulomatous inflammation of the meninges.
我们报告了一例特发性肥厚性硬脑膜炎,患者为一名既往健康的 34 岁菲律宾男性,表现为第三和第六颅神经麻痹、头痛、呕吐和左眼突出。脑部磁共振成像显示弥漫性硬脑膜增厚和强化,伴有轻度脑脊液淋巴细胞增多和轻微蛋白升高。患者接受了抗结核药物和类固醇治疗,恢复良好。我们讨论了脑膜肉芽肿性炎症的鉴别诊断和各种诊断性检查。