Chen Yung-Nien, Mitra Suvobrata
Department of Neurology, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Acta Neurol Taiwan. 2009 Sep;18(3):170-9.
The spatial-verbal dichotomy of working memory tasks was investigated using event-related potentials. Using an n-back task with three levels of n (0-, 1-, and 2-back), participants either matched words presented at a fixed screen position (verbal task) or matched the locations of non-word symbols presented at various positions across the screen (spatial task). Therefore, these two conditions were separated without confound of location and stimulus. Factors of match and task loading (Stimulus and N-Back effect) were found significant in P2a, N2 and P3, whereas domain-specific lateralization (Hemisphere x Task interaction, the feature of perception) was found significant in EPC, P2a and N2 but not in P3. These results hint time course of match (before P2a beginning, 200 ms) and perception (before P3 beginning, 300 ms).
使用事件相关电位研究了工作记忆任务的空间 - 语言二分法。采用具有三个n水平（0 -、1 - 和2 - 回溯）的n - 回溯任务，参与者要么匹配在固定屏幕位置呈现的单词（语言任务），要么匹配在屏幕上不同位置呈现的非单词符号的位置（空间任务）。因此，这两种条件是分开的，不存在位置和刺激的混淆。在P2a、N2和P3中发现匹配和任务负荷因素（刺激和N - 回溯效应）显著，而在EPC、P2a和N2中发现特定领域的侧化（半球×任务交互作用，感知特征）显著，但在P3中不显著。这些结果提示了匹配（在P2a开始前200毫秒）和感知（在P3开始前300毫秒）的时间进程。
