从印度尼西亚海绵 Theonella swinhoei 中分离得到的去氢可可甾醇和金橘酸，这是一种氯化多烯衍生物。

Dehydroconicasterol and aurantoic acid, a chlorinated polyene derivative, from the Indonesian sponge Theonella swinhoei.

机构信息

Dipartimento di Chimica delle Sostanze Naturali, Universita di Napoli Federico II, Via D. Montesano 49, 80131 Napoli, Italy.

出版信息

J Nat Prod. 2009 Dec;72(12):2195-8. doi: 10.1021/np900669d.

DOI:10.1021/np900669d

PMID:19961178

Abstract

The chlorinated polyene aurantoic acid (1) and the 4-methylene sterol dehydroconicasterol (2) were isolated from the Indonesian sponge Theonella swinhoei, and their structures were elucidated by interpretation of spectroscopic data. Aurantoic acid is a unique member in the class of naturally occurring conjugated polyene derivatives, while dehydroconicasterol is the likely biogenetic precursor of the major Theonella 4-methylene sterols.

摘要

从印度尼西亚海绵 Theonella swinhoei 中分离得到了氯代多烯金烯酸（1）和 4-亚甲基甾醇脱氢康甾醇（2），并通过光谱数据分析阐明了它们的结构。金烯酸是天然存在的共轭多烯衍生物类中的一个独特成员，而脱氢康甾醇则可能是 Theonella 4-亚甲基甾醇的主要生物前体。