西尼罗河病毒初次感染多年后持续感染。
Persistent infection with West Nile virus years after initial infection.
机构信息
School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA.
出版信息
J Infect Dis. 2010 Jan 1;201(1):2-4. doi: 10.1086/648731.
Abstract
West Nile virus (WNV) RNA was demonstrated in 5 (20%) of 25 urine samples collected from convalescent patients 573-2452 days (1.6-6.7 years) after WNV infection. Four of the 5 amplicons sequenced showed >99% homology to the WNV NY99 strain. These findings show that individuals with chronic symptoms after WNV infection may have persistent renal infection over several years.
摘要
西尼罗河病毒（WNV）RNA 在 25 份采集于恢复期患者的尿液样本中被检测到，这些患者在感染 WNV 后 573-2452 天（1.6-6.7 年）。测序的 5 个扩增子中有 4 个与 WNV NY99 株具有 >99%的同源性。这些发现表明，WNV 感染后出现慢性症状的个体可能在数年内存在持续性肾脏感染。
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J Virol. 2009 May;83(9):4251-61. doi: 10.1128/JVI.00017-09. Epub 2009 Feb 18.
2
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