使用Identifiler试剂盒的15个短串联重复序列对阿兹鲁说柏柏尔语的人群进行系统发育结构评估。
Assessment of phylogenetic structure of Berber-speaking population of Azrou using 15 STRs of Identifiler kit.
作者信息
El Ossmani Hicham, Bouchrif Brahim, Aboukhalid Rachid, Bouabdillah Mehdi, Gazzaz Bouchaïb, Zaoui Driss, Chafik Abdelaziz, Talbi Jalal
机构信息
Laboratory of Anthropogenetics and Physiopathology, Department of Biology, University of Chouaïb Doukkali, Faculty of Sciences, El Jadida, Morocco.
出版信息
Leg Med (Tokyo). 2010 Jan;12(1):52-6. doi: 10.1016/j.legalmed.2009.10.004. Epub 2009 Dec 4.
Allele frequencies for 15 STR autosomal loci of Identifiler kit (D8S1179, D21S11, D7S820, CSF1PO, D3S1358, TH01, D13S317, D16S539, D2S1338, D19S433, vWA, TPOX, D18S51, D5S818 and FGA) in the Moroccan population of Berber-speaking of Azrou, were assessed from a sample of 201 unrelated individuals. Markers D18S51, D2S1338, FGA and D21S11 present the highest power of discrimination (PD) values while D21S11 was the most polymorphic locus in the studied population. The phylogenetic tree established among worldwide populations, shows that Berber-speaking population of Azrou was so close to the Berber-speaking population of Asni but also to the Arab-speaking population of southern Morocco. Nevertheless, a significant distance was observed between populations of Azrou and Bouhria even they share the same dialect (Amazigh) and belong to the same geographical area (Morocco). The 15 STR loci studied appear to be highly discriminating, thus providing a powerful tool for forensic applications, paternity investigation, individual identification and anthropological studies.
在来自阿兹鲁讲柏柏尔语的摩洛哥人群中，从201名无亲缘关系个体的样本评估了Identifiler试剂盒（D8S1179、D21S11、D7S820、CSF1PO、D3S1358、TH01、D13S317、D16S539、D2S1338、D19S433、vWA、TPOX、D18S51、D5S818和FGA）的15个常染色体STR基因座的等位基因频率。基因座D18S51、D2S1338、FGA和D21S11具有最高的鉴别力（PD）值，而D21S11是研究人群中多态性最高的基因座。在全球人群中建立的系统发育树表明，阿兹鲁讲柏柏尔语的人群与阿斯尼讲柏柏尔语的人群非常接近，也与摩洛哥南部讲阿拉伯语的人群接近。然而，即使阿兹鲁和布赫里亚的人群共享相同的方言（阿马齐格语）且属于同一地理区域（摩洛哥），在它们之间也观察到了显著的差异。所研究的15个STR基因座似乎具有高度鉴别力，因此为法医应用、亲子鉴定调查、个体识别和人类学研究提供了一个强大的工具。
Zotero 插件