摩洛哥南部人群中15个常染色体STR基因座的等位基因频率以及全球人群中的系统发育结构。
Allele frequencies of 15 autosomal STR loci in the southern Morocco population with phylogenetic structure among worldwide populations.
作者信息
Ossmani Hicham El, Talbi Jalal, Bouchrif Brahim, Chafik Abdelaziz
机构信息
Genetics Laboratory of Royal Gendarmery, Avenue Ibn Sina, 10100, Rabat, Morocco.
出版信息
Leg Med (Tokyo). 2009 May;11(3):155-8. doi: 10.1016/j.legalmed.2009.01.053. Epub 2009 Mar 13.
Polymerase chain reaction (PCR) amplification using the AmpFl STR Identifiler kit was performed in a random sample of 204 unrelated individuals from the Arabic-speaking population of the southern Morocco. Allele frequencies of 15 STRs loci (D13S317, D16S539, D2S1338, vWA, TPOX, D18S51, D5S818, FGA, D8S1179, D21S11, D7S820, D19S433, CSF1PO, TH01 and D3S1358) have been reported in this population. Markers D18S51, FGA, D2S1338 and D21S11 had the highest power of discrimination (PD) values while TH01 was the most informative locus in the studied population. The phylogenetic tree established among worldwide populations and genetic distance values show a great affinity between the Southern Moroccan population, Saudian, Moroccan of Asni and Andalusian. Our data is useful for anthropological and other comparative studies of populations and is powerful for forensic and paternity testing in the Arabic-speaking population of the Southern Morocco.
使用AmpFl STR Identifiler试剂盒对来自摩洛哥南部讲阿拉伯语人群的204名无亲缘关系个体的随机样本进行聚合酶链反应（PCR）扩增。已报道了该人群中15个STR基因座（D13S317、D16S539、D2S1338、vWA、TPOX、D18S51、D5S818、FGA、D8S1179、D21S11、D7S820、D19S433、CSF1PO、TH01和D3S1358）的等位基因频率。标记D18S51、FGA、D2S1338和D21S11具有最高的鉴别力（PD）值，而TH01是研究人群中信息最丰富的基因座。在全球人群中建立的系统发育树和遗传距离值显示，摩洛哥南部人群、沙特人、阿斯尼的摩洛哥人和安达卢西亚人之间有很大的亲缘关系。我们的数据对人群的人类学和其他比较研究有用，并且对摩洛哥南部讲阿拉伯语人群的法医鉴定和亲子鉴定很有帮助。
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