International Health, Center for Global Health and Diseases, Case Western Reserve University School of Medicine, 2103 Cornell Road, Wolstein 4126, Cleveland, OH 44106-7286, USA.
Acta Trop. 2010 Feb;113(2):95-104. doi: 10.1016/j.actatropica.2009.11.012. Epub 2009 Dec 4.
Simultaneous and sequential transmission of multiple parasites, and their resultant overlapping chronic infections, are facts of life in many underdeveloped rural areas. These represent significant but often poorly measured health and economic burdens for affected populations. For example, the chronic inflammatory process associated with long-term schistosomiasis contributes to anaemia and undernutrition, which, in turn, can lead to growth stunting, poor school performance, poor work productivity, and continued poverty. To date, most national and international programs aimed at parasite control have not considered the varied economic and ecological factors underlying multi-parasite transmission, but some are beginning to provide a coordinated approach to control. In addition, interest is emerging in new studies for the re-evaluation and recalibration of the health burden of helminthic parasite infection. Their results should highlight the strong potential of integrated parasite control in efforts for poverty reduction.
在许多欠发达的农村地区,多种寄生虫同时或相继传播,并导致其重叠性慢性感染,是一种常见现象。这些寄生虫对受影响人群的健康和经济造成了重大负担,但往往未得到充分重视和准确评估。例如,长期感染血吸虫病所导致的慢性炎症过程可导致贫血和营养不良,进而导致生长迟缓、学习成绩不佳、工作能力低下和持续贫困。迄今为止,大多数旨在控制寄生虫的国家和国际项目都没有考虑到多寄生虫传播背后的各种经济和生态因素,但有些项目开始提供控制寄生虫的综合方法。此外,人们对重新评估和重新调整寄生虫感染所致卫生负担的新研究也产生了兴趣。这些研究结果应该突出寄生虫综合控制在减贫工作中的巨大潜力。