Fu Y, Ijare O, Thomas G, Fazel-Rezai R, Serrai H
Institute for Biodiagnostics (IBD), NRC, Winnipeg, MB, Canada., Canada.
Annu Int Conf IEEE Eng Med Biol Soc. 2009;2009:2688-91. doi: 10.1109/IEMBS.2009.5332453.
Proton magnetic resonance spectroscopic imaging (MRSI) provides spatial information about tissue metabolite concentrations used in differentiating diseased from normal tissue. Obtaining metabolic maps with high spatial resolution requires long acquisition time where the patient has to lie still inside the magnet bore (scanner) especially if classical Chemical Shift Imaging (CSI) is used. To reduce acquisition time and obtain a more accurate metabolite distribution with low voxel contamination in MRSI, we have recently proposed and successfully implemented a full Wavelet Encoding-Spectroscopic Imaging (WE-SI) technique on a 1.5 Tesla whole body MR clinical scanner. In this paper we describe the implementation of the WE-SI technique at higher magnetic field strength (B(0)) on a clinical 3 Tesla Siemens scanner equipped with parallel imaging tools for better sensitivity. This increases the signal to noise ratio (SNR) and allows combination of the proposed technique with the so-called parallel imaging approach for further acquisition time reduction.
质子磁共振波谱成像(MRSI)可提供有关组织代谢物浓度的空间信息,用于区分病变组织和正常组织。获得具有高空间分辨率的代谢图谱需要较长的采集时间,在此期间患者必须静止不动地躺在磁体孔(扫描仪)内,尤其是在使用经典化学位移成像(CSI)的情况下。为了减少采集时间并在MRSI中获得具有低体素污染的更准确代谢物分布,我们最近在一台1.5特斯拉全身MR临床扫描仪上提出并成功实施了全小波编码波谱成像(WE-SI)技术。在本文中,我们描述了在配备有并行成像工具以提高灵敏度的临床3特斯拉西门子扫描仪上,在更高磁场强度(B(0))下实施WE-SI技术的情况。这增加了信噪比(SNR),并允许将所提出的技术与所谓的并行成像方法相结合,以进一步减少采集时间。