Yadollahi Azadeh, Moussavi Zahra
Department of Electrical and Computer Engineering, University of Manitoba, Winnipeg, MB, Canada, R3T 5V6.
Annu Int Conf IEEE Eng Med Biol Soc. 2009;2009:7110-3. doi: 10.1109/IEMBS.2009.5332870.
Obstructive sleep apnea (OSA) is a common respiratory disorder during sleep, in which the airways are collapsed and impair the respiration. Apnea is s cessation of airflow to the lungs which lasts at least for 10s. The current gold standard method for OSA assessment is full night polysomnography (PSG); however, its high cost, inconvenience for patients and immobility have persuaded researchers to seek simple and portable devices to detect OSA. In this paper, we report on developing a new system for OSA detection and monitoring, which only requires two data channels: tracheal breathing sounds and the blood oxygen saturation level (S(a)O(2)). A fully automated method was developed that uses the energy of breathing sounds signals to segment the signals into sound and silent segments. Then, the sound segments are classified into breath, snore (if exists) and noise segments. The S(a)O(2) signal is analyzed to find the rises and drops in the S(a)O(2) signal. Finally, a fuzzy algorithm was developed to use this information and detect apnea and hypopnea events. The method was evaluated on the data of 40 patients simultaneously with full night PSG study, and the results were compared with those of the PSG. The results show high correlation (96%) between our system and PSG. Also, the method has been found to have sensitivity and specificity values of more than 90% in differentiating simple snorers from OSA patients.
阻塞性睡眠呼吸暂停(OSA)是一种常见的睡眠期间呼吸系统疾病,在此疾病中气道会塌陷并损害呼吸功能。呼吸暂停是指气流停止进入肺部至少持续10秒。目前用于OSA评估的金标准方法是全夜多导睡眠图(PSG);然而,其高昂的成本、给患者带来的不便以及患者需保持静止等因素促使研究人员寻求简单且便携的设备来检测OSA。在本文中,我们报告了一种用于OSA检测和监测的新系统的开发情况,该系统仅需要两个数据通道:气管呼吸音和血氧饱和度水平(S(a)O(2))。我们开发了一种全自动方法,利用呼吸音信号的能量将信号分割为有声段和无声段。然后,将有声段分类为呼吸、打鼾(如果存在)和噪声段。对S(a)O(2)信号进行分析以找出S(a)O(2)信号中的上升和下降情况。最后,开发了一种模糊算法来利用这些信息检测呼吸暂停和呼吸不足事件。该方法在40名患者的数据上与全夜PSG研究同时进行了评估,并将结果与PSG的结果进行了比较。结果表明我们的系统与PSG之间具有高度相关性(96%)。此外,该方法在区分单纯打鼾者和OSA患者方面的灵敏度和特异度值均超过90%。