Wen Jing, Wang Xishu, Kibbe Warren, Lin Simon, Lu Hui
Department of Bioengineering, University of Illinois at Chicago, Chicago, IL 60607, USA.
Annu Int Conf IEEE Eng Med Biol Soc. 2009;2009:4175-7. doi: 10.1109/IEMBS.2009.5333931.
The genes in NCBI databases are currently annotated with itemized text (Gene Reference Into Function, or GeneRIF). A previous work suggests that the visual presentation can be more effective when time and space are under heavy constraints. Here we report a novel annotation of the genome information using Web 2.0 technologies: GeneGIF (Gene Graphics Into Function). The users can quickly scan through important functions of each gene from a graph, and then go to detailed pages when they find interesting annotations. The modular implementation makes it easily pluggable into other widely used databases without reprogramming. Similar approaches are being developed to incorporate information to other types of genomics and proteomics databases.
NCBI数据库中的基因目前用逐条文本（基因功能参考，即GeneRIF）进行注释。先前的一项研究表明，在时间和空间受到严格限制时，可视化展示可能会更有效。在此，我们报告一种使用Web 2.0技术对基因组信息进行的全新注释：GeneGIF（基因图形化功能注释）。用户可以通过一张图表快速浏览每个基因的重要功能，然后在发现感兴趣的注释时转到详细页面。模块化实现方式使其无需重新编程就能轻松插入其他广泛使用的数据库。正在开发类似的方法，以便将信息整合到其他类型的基因组学和蛋白质组学数据库中。
