Lott Gus K, Johnson Bruce R, Bonow Robert H, Land Bruce R, Hoy Ronald R
Howard Hughes Medical Instituted, Janelia farm Research Campus, 19700 Helix Dr, Ashburn, VA 20147, USA.
Annu Int Conf IEEE Eng Med Biol Soc. 2009;2009:2019-21. doi: 10.1109/IEMBS.2009.5334424.
We report on the real-time creation of an application for hands-on neurophysiology in an advanced undergraduate teaching laboratory. Enabled by the rapid software development tools included in the Matlab technical computing environment (The Mathworks, Natick, MA), a team, consisting of a neurophysiology educator and a biophysicist trained as an electrical engineer, interfaced to a course of approximately 15 students from engineering and biology backgrounds. The result is the powerful freeware data acquisition and analysis environment, "g-PRIME." The software was developed from week to week in response to curriculum demands, and student feedback. The program evolved from a simple software oscilloscope, enabling RC circuit analysis, to a suite of tools supporting analysis of neuronal excitability and synaptic transmission analysis in invertebrate model systems. The program has subsequently expanded in application to university courses, research, and high school projects in the US and abroad as free courseware.
我们报告了在一个高级本科教学实验室中实时创建一个用于实践神经生理学的应用程序的情况。在Matlab技术计算环境（Mathworks公司，马萨诸塞州纳蒂克）中包含的快速软件开发工具的支持下，一个由神经生理学教育工作者和一名接受过电气工程师培训的生物物理学家组成的团队，与大约15名来自工程和生物学背景的学生组成的课程进行了对接。结果是产生了强大的免费数据采集和分析环境“g-PRIME”。该软件根据课程需求和学生反馈逐周开发。该程序从一个简单的软件示波器发展而来，最初用于RC电路分析，后来演变成一套支持对无脊椎动物模型系统中的神经元兴奋性和突触传递分析的工具。该程序随后作为免费课程软件在美国和国外的大学课程、研究以及高中项目中得到了更广泛的应用。
