National University Hospital, 119074, Singapore.
Cancer Imaging. 2009 Oct 2;9 Spec No A(Special issue A):S14-21. doi: 10.1102/1470-7330.2009.9004.
Primary malignant tumours arising from the meninges are distinctly uncommon, and when they occur, they are usually sarcomas. In contrast, metastatic meningeal involvement is increasingly seen as advances in cancer therapy have changed the natural history of malignant disease and prolonged the life span of cancer patients. The meninges can either be infiltrated by contiguous extension of primary tumours of the central nervous system, paranasal sinuses and skull base origin or can be diffusely infiltrated from haematogenous dissemination from distant primary malignancies. Imaging in these patients provides crucial information in planning management. This article reviews the pertinent anatomy that underlies imaging findings, discusses the mechanism of meningeal metastasis and highlights different imaging patterns of meningeal carcinomatosis and the pitfalls.
原发于脑膜的恶性肿瘤极为罕见,且通常为肉瘤。相反,随着癌症治疗的进步改变了恶性疾病的自然病程并延长了癌症患者的生存期,因此脑膜转移越来越常见。脑膜可以通过中枢神经系统、副鼻窦和颅底原发性肿瘤的连续扩展进行浸润,也可以通过远处原发性恶性肿瘤的血行播散进行弥漫性浸润。这些患者的影像学检查为制定治疗计划提供了重要信息。本文回顾了与影像学表现相关的解剖基础,讨论了脑膜转移的机制,并强调了脑膜癌病的不同影像学模式和陷阱。