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Ahmed 青光眼阀治疗难治性青光眼:7 年回顾性研究。

Ahmed glaucoma valves in refractory glaucoma: a 7-year audit.

机构信息

St Paul's Eye Unit, Royal Liverpool University Hospital, Prescot Street, Liverpool L7 8XP, UK.

出版信息

Br J Ophthalmol. 2010 Sep;94(9):1174-9. doi: 10.1136/bjo.2009.165357. Epub 2009 Dec 3.

Abstract

PURPOSE

To present the long-term results of Ahmed glaucoma valve (AGV) implantation.

METHODS

Consecutive case series of 94 eyes with AGV implantation over 7 years. Temporary tube ligation with C3F8 gas fill was used in high-risk eyes (group G&L) and compared with standard implantation in both phakic (group A) and pseudophakic/aphakic eyes (group B). Success was intraocular pressure (IOP) of 6 mm Hg or greater and 21 mm Hg or less and/or IOP reduction of 20% or greater.

RESULTS

Average follow-up was 28.9+/-20.3 months. The mean preoperative IOP changed from 30.8+/-8.2 to 19.7+/-7.6 mm Hg and mean preoperative medications changed from 3.3+/-1.2 to 1.2+/-1.1 at the final visit. Cumulative probability of survival at 1 and 4 years was 89.1% and 72.9%. There was no statistically significant difference in success between the three groups, but complications due to postoperative hypotony (six eyes) only occurred in group B. Other complications were corneal decompensation (three eyes), tube erosion (six eyes) and aqueous misdirection (four eyes).

CONCLUSIONS

AGV implantation offered good long-term IOP control with a success rate of 78.7%. The authors recommend C3F8 gas fill and temporary tube ligation in eyes at high risk of postoperative hypotony and the use of donor sclera or human pericardial patch to prevent tube erosion.

摘要

目的

介绍 Ahmed 青光眼阀(AGV)植入的长期结果。

方法

对 7 年内连续 94 例接受 AGV 植入的病例进行了回顾性系列研究。高危眼(G&L 组)采用临时管结扎联合 C3F8 气体填充,与有晶状体眼(A 组)和无晶状体/人工晶状体眼(B 组)的标准植入进行比较。成功标准为眼压(IOP)为 6mmHg 或更高且 21mmHg 或更低,或 IOP 降低 20%或更多。

结果

平均随访 28.9+/-20.3 个月。平均术前 IOP 从 30.8+/-8.2mmHg 降至 19.7+/-7.6mmHg,最终随访时平均术前用药从 3.3+/-1.2 降至 1.2+/-1.1。1 年和 4 年的累积生存率分别为 89.1%和 72.9%。三组间成功率无统计学差异,但仅在 B 组发生了与术后低眼压相关的并发症(六只眼)。其他并发症包括角膜失代偿(三只眼)、引流管侵蚀(六只眼)和房水引流异常(四只眼)。

结论

AGV 植入术可获得良好的长期眼压控制,成功率为 78.7%。作者建议在术后易发生低眼压的高危眼中使用 C3F8 气体填充和临时管结扎,并使用供体巩膜或心包补片来预防引流管侵蚀。

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