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Immune modulation: Turncoat regulatory T cells.

作者信息

Gadina Massimo, O'Shea John J

机构信息

Translational Immunology Section, National Institute of Arthritis, Musculoskeletal and Skin Diseases, Bethesda, Maryland, USA.

出版信息

Nat Med. 2009 Dec;15(12):1365. doi: 10.1038/nm1209-1365.

DOI:10.1038/nm1209-1365
PMID:19966774
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2994186/
Abstract
摘要

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Nat Immunol. 2009 Sep;10(9):1000-7. doi: 10.1038/ni.1774. Epub 2009 Jul 26.
2
Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor.表达FoxP3转录因子的人CD4+ T细胞的功能划分与分化动力学
Immunity. 2009 Jun 19;30(6):899-911. doi: 10.1016/j.immuni.2009.03.019. Epub 2009 May 21.
3
The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation.转录因子T-bet在1型炎症期间控制调节性T细胞的稳态和功能。
Nat Immunol. 2009 Jun;10(6):595-602. doi: 10.1038/ni.1731. Epub 2009 May 3.
4
Preferential generation of follicular B helper T cells from Foxp3+ T cells in gut Peyer's patches.肠道派尔集合淋巴结中Foxp3+ T细胞优先生成滤泡辅助性B细胞。
Science. 2009 Mar 13;323(5920):1488-92. doi: 10.1126/science.1169152.
5
Heterogeneity of natural Foxp3+ T cells: a committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity.天然Foxp3+ T细胞的异质性：一个已分化的调节性T细胞谱系和一个未分化的具有可塑性的少数群体。
Proc Natl Acad Sci U S A. 2009 Feb 10;106(6):1903-8. doi: 10.1073/pnas.0811556106. Epub 2009 Jan 27.
6
Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells.H3K4me3和H3K27me3的全基因组图谱揭示了分化中的CD4+ T细胞谱系命运决定的特异性和可塑性。
Immunity. 2009 Jan 16;30(1):155-67. doi: 10.1016/j.immuni.2008.12.009.
7
Epigenetic control of FOXP3 expression: the key to a stable regulatory T-cell lineage?FOXP3表达的表观遗传调控：稳定调节性T细胞谱系的关键？
Nat Rev Immunol. 2009 Feb;9(2):83-9. doi: 10.1038/nri2474.
8
Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity.调节性T细胞中miRNA的选择性破坏会导致不受控制的自身免疫。
J Exp Med. 2008 Sep 1;205(9):1983-91. doi: 10.1084/jem.20080707. Epub 2008 Aug 25.
9
In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ RORgamma t+ T cells.促炎性白细胞介素-17+和调节性白细胞介素-10+、叉头框蛋白3+、维甲酸相关孤儿受体γt+T细胞的体内平衡
J Exp Med. 2008 Jun 9;205(6):1381-93. doi: 10.1084/jem.20080034. Epub 2008 May 26.