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奶山羊群中的氨基甲酸酯中毒:临床病理检查结果及治疗方法

Carbamate poisoning in a dairy goat herd: clinicopathological findings and therapeutic approach.

作者信息

Giadinis N D, Raikos N, Loukopoulos P, Malliarakis E, Karatzias H

机构信息

Clinic of Farm Animals, School of Veterinary Medicine, Aristotle University of Thessaloniki, 11 St Voutyra Street, 546 27 Thessaloniki, Greece.

出版信息

N Z Vet J. 2009 Dec;57(6):392-4. doi: 10.1080/00480169.2009.64735.

DOI:10.1080/00480169.2009.64735
PMID:19966902
Abstract

CASE HISTORY

Approximately 1 hour after the consumption of carnations from a nearby glasshouse 55 animals from a dairy goat herd exhibited signs of possible poisoning.

CLINICAL FINDINGS

Upon clinical examination affected animals exhibited signs of salivation, tympany, tachypnoea, polydipsia, urination, diarrhoea, bradycardia, miosis, tremor and convulsions. As poisoning from an acetylcholinesterase-inhibiting insecticide was suspected, treatment with atropine sulphate was initiated at a dose of 0.3 mg/kg bodyweight. The treatment was repeated for some animals that relapsed, and was effective in all cases, with the exception of one goat kid that died.

DIAGNOSIS

Necropsy of the goat kid showed pulmonary oedema and congestion of internal organs. Toxicological analysis of stomach contents and liver of the dead animal, as well as of the carnations, revealed high concentrations of carbamates.

CLINICAL RELEVANCE

Carbamate poisoning after consumption of polluted feedstuffs or glasshouse products can be fatal for dairy goats. Atropine sulphate, at 0.3 mg/kg, can be useful in treating this condition.

摘要

病例史

一群奶山羊中的55只动物在食用了附近温室种植的康乃馨约1小时后,出现了可能中毒的症状。

临床发现

经临床检查,受影响的动物表现出流涎、鼓胀、呼吸急促、多饮、排尿、腹泻、心动过缓、瞳孔缩小、震颤和惊厥等症状。由于怀疑是乙酰胆碱酯酶抑制性杀虫剂中毒,开始以0.3毫克/千克体重的剂量用硫酸阿托品进行治疗。一些复发的动物重复进行了治疗,除一只死亡的山羊羔外,所有病例均有效。

诊断

对死亡的山羊羔进行尸检,发现肺水肿和内脏充血。对死亡动物的胃内容物和肝脏以及康乃馨进行毒理学分析,发现含有高浓度的氨基甲酸盐。

临床意义

食用受污染的饲料或温室产品后发生氨基甲酸盐中毒,可能会导致奶山羊死亡。0.3毫克/千克的硫酸阿托品可用于治疗这种情况。

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