Wilkinson D J
Department of Anaesthesia, St. Bartholomew's Hospital, West Smithfield, London.
Anaesthesia. 1991 Jan;46(1):49-51. doi: 10.1111/j.1365-2044.1991.tb09317.x.
Curare was used in the 19th century in England by a wide variety of scientists, physicians and veterinarians. Their experiments indicated many of the properties of the drug, but its clinical usage remained very limited and was reserved for cases of tetanus, hydrophobia and strychnine poisoning. Griffith and Johnson are usually credited with the introduction of curare into clinical anaesthesia in 1942, but a Dr F.P. de Caux working at the North Middlesex Hospital, London, in 1928 utilised curare in a series of seven patients. His work was not widely publicized and this contribution to anaesthetic history has been overlooked by subsequent authors.
19世纪,箭毒在英国被众多科学家、医生和兽医使用。他们的实验揭示了这种药物的许多特性,但其临床应用仍然非常有限,仅用于破伤风、狂犬病和士的宁中毒病例。通常认为是格里菲斯和约翰逊在1942年将箭毒引入临床麻醉,但1928年在伦敦北米德尔塞克斯医院工作的F.P. 德考克斯医生曾在7名患者身上使用过箭毒。他的工作没有得到广泛宣传,后续作者也忽略了他对麻醉史的这一贡献。