Clinic of Children Diseases, Kaunas University of Medicine, Kaunas, Lithuania.
J Nephrol. 2009 Nov-Dec;22(6):766-73.
To determine urodynamic, behavioral and functional abnormalities predisposing to recurrent urinary tract infection in 5- to 17-year-old girls.
A prospective case-control study was carried out. A total of 148 girls met inclusion criteria. They received a careful evaluation including complete history, voiding-drinking diary, bowel questionnaire, physical investigation, sonography, voiding cystourethrogram and urodynamic investigation.
In a multivariate model, independent risk factors for recurrent urinary tract infection included age <or=6.5 years at first urinary tract infection (odds ratio [OR] = 0.9; 95% confidence interval [95% CI], 0.85-0.98), abnormal voiding frequency (OR=5.3; 95% CI, 1.1-26.2), voiding postponement (OR=3.8; 95% CI, 1.4-10.1), poor fluid intake (OR=9.2; 95% CI, 2.5-33.6) and residual urine volume of >20 mL (OR=1.1; 95% CI, 1.0-1.1).
Independent risk factors for recurrent urinary tract infection were age <or=6.5 years at first urinary tract infection, abnormal voiding frequency, voiding postponement, poor fluid intake and residual urine. Our results indicate that none of the urodynamic factors was significantly associated with recurrence of urinary tact infection in girls.
确定易导致 5 至 17 岁女孩复发性尿路感染的尿动力学、行为和功能异常。
进行了一项前瞻性病例对照研究。共有 148 名女孩符合纳入标准。她们接受了详细的评估，包括完整的病史、排尿-饮水日记、排便问卷、体格检查、超声检查、排尿性膀胱尿道造影和尿动力学检查。
在多变量模型中，复发性尿路感染的独立危险因素包括首次尿路感染时年龄≤6.5 岁（比值比 [OR] = 0.9；95%置信区间 [95%CI]，0.85-0.98）、排尿频率异常（OR=5.3；95%CI，1.1-26.2）、排尿延迟（OR=3.8；95%CI，1.4-10.1）、液体摄入不足（OR=9.2；95%CI，2.5-33.6）和残余尿量＞20 mL（OR=1.1；95%CI，1.0-1.1）。
首次尿路感染时年龄≤6.5 岁、排尿频率异常、排尿延迟、液体摄入不足和残余尿是复发性尿路感染的独立危险因素。我们的结果表明，尿动力学因素均与女孩尿路感染的复发无显著相关性。
