Department of Psychology, University of Western Ontario, Westminster Hall, London, Ontario N6A 3K7, Canada.
J Consult Clin Psychol. 2009 Dec;77(6):1078-88. doi: 10.1037/a0016886.
Negative cognitive structure (particularly for interpersonal content) has been shown in some research to persist past a current episode of depression and potentially to be a stable marker of vulnerability for depression (D. J. A. Dozois, 2007; D. J. A. Dozois & K. S. Dobson, 2001a). Given that cognitive therapy (CT) is highly effective for treating the acute phase of a depressive episode and that this treatment also reduces the risk of relapse and recurrence, it is possible that CT may alter these stable cognitive structures. In the current study, patients were randomly assigned to CT+ pharmacotherapy (n = 21) or to pharmacotherapy alone (n = 21). Both groups evidenced significant and similar reductions in level of depression (as measured with the Beck Depression Inventory-II and the Hamilton Rating Scale for Depression), as well as automatic thoughts and dysfunctional attitudes. However, group differences were found on cognitive organization in favor of individuals who received the combination of CT+ pharmacotherapy. The implications of these results for understanding mechanisms of change in therapy and the prophylactic nature of CT are discussed.
负面认知结构（特别是人际内容）在一些研究中被证明在当前抑郁发作后仍然存在，并可能成为抑郁易感性的稳定标志物（D. J. A. Dozois，2007；D. J. A. Dozois & K. S. Dobson，2001a）。鉴于认知疗法（CT）对治疗抑郁发作的急性期非常有效，并且这种治疗还降低了复发和复发的风险，因此 CT 可能会改变这些稳定的认知结构。在当前的研究中，患者被随机分配到 CT+药物治疗组（n = 21）或单独药物治疗组（n = 21）。两组在抑郁程度（贝克抑郁量表二和汉密尔顿抑郁评定量表）、自动思维和功能失调态度上都有显著且相似的降低。然而，在认知组织方面发现了组间差异，有利于接受 CT+药物联合治疗的个体。讨论了这些结果对理解治疗机制变化和 CT 预防性的意义。
