Department of Psychiatry, Columbia University/New York State Psychiatric Institute, New York, NY 10032, USA.
Harv Rev Psychiatry. 2009;17(6):377-88. doi: 10.3109/10673220903463333.
In this article we review the role of depression and other related psychological factors in heart disease. The prevalence of heart disease in patients with depression is high, and epidemiological links between depression and heart disease are evident in studies of community samples, psychiatric patients, and heart disease patients. We also describe the links between heart disease and related psychological factors-including vital exhaustion, Type A behavior pattern, anger and hostility, and Type D personality-and summarize proposed mechanisms that may link negative affects with heart disease. Finally, we review treatment of depression in heart disease, including evidence from several large clinical trials.
本文回顾了抑郁和其他相关心理因素在心脏病中的作用。患有抑郁症的心脏病患者的发病率很高，在对社区样本、精神病人和心脏病患者的研究中，抑郁和心脏病之间存在明显的流行病学联系。我们还描述了心脏病与相关心理因素（包括心力耗竭、A型行为模式、愤怒和敌意以及 D 型人格）之间的联系，并总结了可能将负性情绪与心脏病联系起来的机制。最后，我们回顾了心脏病患者的抑郁治疗，包括几项大型临床试验的证据。
