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认识并应对美国的恰加斯病挑战。

Recognizing and meeting the challenge of Chagas disease in the USA.

机构信息

Infectious Diseases Fellow University of Texas Health Science Center San Antonio, Mail Code 7881, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA.

出版信息

Expert Rev Anti Infect Ther. 2009 Dec;7(10):1223-34. doi: 10.1586/eri.09.107.

DOI:10.1586/eri.09.107
PMID:19968514
Abstract

It is estimated that over 300,000 people with Chagas disease are living in the USA, with more than 30,000 cases of Chagas cardiomyopathy expected per year. The epidemiology of Chagas disease in Central and South America differs from that of the USA, where particular attention must focus on blood bank screening, organ donation and vertical transmission. It is essential that healthcare practitioners have heightened awareness of Chagas disease in the differential diagnosis of certain patients and are aware of recommendations for the management of these patients in the USA. Ongoing attention must focus on trials that determine whether all patients will benefit from treatment as well as studies of new agents for therapy.

摘要

据估计,美国有超过 30 万人患有恰加斯病,每年预计有超过 3 万例恰加斯心肌病。中美洲和南美洲的恰加斯病流行病学与美国不同,在美国,必须特别关注血库筛查、器官捐赠和垂直传播。医疗保健从业者在某些患者的鉴别诊断中必须高度警惕恰加斯病,并了解美国管理这些患者的建议。必须持续关注确定所有患者是否都将从治疗中受益的试验,以及研究新的治疗药物。

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Recognizing and meeting the challenge of Chagas disease in the USA.认识并应对美国的恰加斯病挑战。
Expert Rev Anti Infect Ther. 2009 Dec;7(10):1223-34. doi: 10.1586/eri.09.107.
2
Chagas disease. American trypanosomiasis.恰加斯病。美洲锥虫病。
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3
[Recommendations for diagnosis, treatment and follow-up of the Trypanosoma cruzi: human immunodeficiency virus co-infection].[克氏锥虫与人类免疫缺陷病毒合并感染的诊断、治疗及随访建议]
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Antitrypanosomal therapy for chronic Chagas' disease.慢性恰加斯病的抗锥虫治疗。
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[Treatment of Chagas' disease].[恰加斯病的治疗]
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[Nifurtimox, a bright future for treatment of Chagas disease].[硝呋替莫,恰加斯病治疗的光明未来]
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Selective decrease of components of the creatine kinase system and ATP synthase complex in chronic Chagas disease cardiomyopathy.选择性降低慢性恰加斯病心肌病中肌酸激酶系统和 ATP 合酶复合物的成分。
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