慢性精神分裂症患者的精神病理学症状和认知功能与主观生活质量的关系。
Relationship of psychopathological symptoms and cognitive function to subjective quality of life in patients with chronic schizophrenia.
机构信息
Department of Psychiatry, Nagoya University, Graduate School of Medicine, Aichi, Japan.
出版信息
Psychiatry Clin Neurosci. 2010 Feb;64(1):62-9. doi: 10.1111/j.1440-1819.2009.02033.x. Epub 2009 Nov 24.
AIMS
The purpose of the present study was to examine the extent of the effects of psychopathological symptoms and cognitive function on quality of life (QOL) in patients with chronic schizophrenia.
METHODS
Data were obtained using the Japanese Schizophrenia Quality of Life Scale (JSQLS), Positive and Negative Syndrome Scale (PANSS), Wisconsin Card-Sorting Test (WCST) Keio version, and Continuous Performance Test (CPT) for 52 schizophrenia patients.
RESULTS
Stepwise regression analysis showed that PANSS depression/anxiety factors predicted JSQLS psychosocial conditions and motivation/energy, and that WCST Categories Achieved predicted JSQLS symptoms/side-effects.
CONCLUSIONS
Psychopathological symptoms and cognitive function affect subjective QOL in patients with schizophrenia. If the final goal is treatment that improves QOL in a manner that patients themselves are aware of, clinicians probably need to consider a treatment strategy that improves depression/anxiety symptom.
目的
本研究旨在探讨精神病理症状和认知功能对慢性精神分裂症患者生活质量（QOL）的影响程度。
方法
本研究使用日本精神分裂症生活质量量表（JSQLS）、阳性和阴性症状量表（PANSS）、日本版威斯康星卡片分类测验（WCST）和连续操作测验（CPT）对 52 名精神分裂症患者进行了数据收集。
结果
逐步回归分析表明，PANSS 抑郁/焦虑因子预测了 JSQLS 的心理社会状况和动机/能量，而 WCST 完成的类别预测了 JSQLS 的症状/副作用。
结论
精神病理症状和认知功能影响精神分裂症患者的主观 QOL。如果最终目标是以患者自身能够意识到的方式改善 QOL 的治疗，那么临床医生可能需要考虑一种改善抑郁/焦虑症状的治疗策略。
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