Biomedical Research Centre, School of Medicine Health Policy and Practice, University of East Anglia, Norwich, UK.
Zoonoses Public Health. 2011 Feb;58(1):60-8. doi: 10.1111/j.1863-2378.2009.01294.x.
Avian influenza A (H5N1) has spread to the UK causing outbreaks in commercial poultry. Vaccination of poultry workers with seasonal influenza has been advised to prevent a viral mutation that could facilitate human-to-human transmission, causing a new pandemic strain. This project aimed to determine delivery options and costs of a vaccination programme targeted at poultry workers. Data from the Great Britain Poultry Register were used to understand the distribution of the target population. A stakeholders group in the East of England (EoE) discussed delivery options. An options appraisal is used to prioritize these options. There are over 10,000 poultry workers distributed throughout the EoE. Five delivery options were considered (industry's occupational health services, via general practitioners as a Directed or Locally Enhanced Services, via other community healthcare providers and a commercial provider). Delivery is likely to cost between £35,414 and £182,899 (or £10.18-£48.93 per person vaccinated) in the EoE, depending on delivery mechanism, target threshold and level of uptake. Delivering through a commercial provider was the preferred option. Whichever way the programme is delivered it should be cost-neutral to the Primary Care Trust (PCT). Otherwise PCTs may see themselves having to prioritize between vaccinating poultry workers against other pressing programmes.
禽流感 A（H5N1）已传播到英国，导致商业家禽中爆发疫情。建议对家禽工人进行季节性流感疫苗接种，以防止病毒突变，从而促进人际传播，引发新的大流行株。本项目旨在确定针对家禽工人的疫苗接种计划的交付方案和成本。使用来自英国家禽登记处的数据来了解目标人群的分布情况。英格兰东部的一个利益相关者小组讨论了交付方案。应用方案评估来对这些方案进行优先排序。在英格兰东部，有超过 10000 名家禽工人。考虑了五种交付方案（行业的职业健康服务、通过全科医生作为定向或增强服务、通过其他社区医疗保健提供者以及商业提供商）。根据交付机制、目标阈值和接种率，在英格兰东部，交付成本可能在 35414 英镑至 182899 英镑之间（或每人接种疫苗 10.18 英镑至 48.93 英镑）。通过商业提供商进行交付是首选方案。无论该计划以何种方式交付，都应对基础保健信托基金（PCT）保持成本中性。否则，PCT 可能会发现自己必须在为家禽工人接种疫苗和其他紧迫的计划之间进行优先排序。
