Paediatric Medical Unit, Southampton General Hospital, Tremona Road, Southampton S016 6YD, UK.
Proc Nutr Soc. 2010 Feb;69(1):174-7. doi: 10.1017/S0029665109991820. Epub 2009 Dec 8.
Of the individuals who present with Crohn's disease 25% are <18 years of age, mostly adolescent. Nutritional impairment and delayed growth are common at diagnosis and remain an issue during the disease course. Treatment has the primary aim to control symptoms, induce disease remission and achieve normal growth in the long term and includes nutritional support and early use of immunomodulation. Puberty may be discordant and is generally late and final adult height may not be achieved until the late teenage years. Chronic ill health and delayed growth may be accompanied by emotional and intellectual immaturity. These factors, including the varying rates of physical and emotional development, need to be considered during adolescence with multidisciplinary input to ensure that the young patient is appropriately supported. Transition to adult care requires close collaboration between paediatric and healthcare teams with careful attention to nutritional, emotional and educational issues, all of which are relevant in the progression from childhood, through adolescence and to adult life.
在出现克罗恩病的人群中，25%的患者年龄<18 岁，大多数为青少年。在诊断时，营养损害和生长迟缓很常见，在疾病过程中仍然是一个问题。治疗的主要目的是控制症状、诱导疾病缓解并实现长期的正常生长，包括营养支持和早期使用免疫调节。青春期可能不协调，通常较晚，直到青少年后期才能达到最终的成年身高。慢性健康不良和生长迟缓可能伴随着情感和智力不成熟。在青少年时期，需要多学科的参与，考虑到这些因素，包括身体和情感发展的不同速度，以确保年轻患者得到适当的支持。向成人护理的过渡需要儿科和医疗团队之间的密切合作，并仔细关注营养、情感和教育问题，这些问题在从儿童期、青春期到成年期的发展过程中都很重要。
