Department of Surgery, Texas Tech University Health Sciences Center, Lubbock, TX, USA.
Am J Surg. 2009 Dec;198(6):787-91. doi: 10.1016/j.amjsurg.2009.05.031.
It is widely accepted that mastectomy and breast-conserving surgery (BCS) with irradiation yield similar results, yet many women continue to receive mastectomy. This study evaluates factors contributing to surgical decision-making in breast cancer. Registry data were obtained on all patients treated at the Southwest Cancer Treatment and Research Center (SWCTRC) between 2002 and 2006. Patient demographics, including age and race, and insurance type, tumor characteristics, surgical procedure performed, lymph node status, stage, adjuvant therapy, and outcome were analyzed against mastectomy versus BCS using bivariate and multivariate analysis.
There was a higher proportion of uninsured patients in the mastectomy cohort, which also included more patients with later stage disease, larger tumor size, and a higher number of lymph node metastases. The only independent predictors of BCS were fewer lymph node metastases and having insurance. Patients with private insurance were almost 4 times more likely to receive BCS (odds ratio 3.90, 95% confidence interval 1.20-12.67).
Insurance status is an important predictor determining whether a patient receives BCS or mastectomy for breast cancer.
广泛认为乳房切除术和保乳手术(BCS)加放疗的效果相似,但仍有许多女性选择接受乳房切除术。本研究旨在评估乳腺癌手术决策的相关因素。
研究人员获取了 2002 年至 2006 年间在西南癌症治疗与研究中心(SWCTRC)接受治疗的所有患者的注册数据。利用单变量和多变量分析,对患者的人口统计学特征(包括年龄和种族)、保险类型、肿瘤特征、手术方式、淋巴结状态、分期、辅助治疗和预后与乳房切除术或 BCS 进行了对比。
乳房切除术组中无保险患者的比例更高,且该组中晚期疾病、肿瘤更大、淋巴结转移更多的患者比例也更高。BCS 的唯一独立预测因素是淋巴结转移较少和有保险。有私人保险的患者接受 BCS 的可能性几乎是没有保险患者的 4 倍(优势比 3.90,95%置信区间 1.20-12.67)。
保险状况是决定患者接受乳腺癌保乳手术还是乳房切除术的一个重要预测因素。