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癌症疼痛中的镇痛药:当前的实践与认知

Analgesics in cancer pain: current practice and beliefs.

作者信息

White I D, Hoskin P J, Hanks G W, Bliss J M

机构信息

Royal Marsden Hospital, London, UK.

出版信息

Br J Cancer. 1991 Feb;63(2):271-4. doi: 10.1038/bjc.1991.63.

DOI:10.1038/bjc.1991.63
PMID:1997105
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1971781/
Abstract

Prescribing practices for patients with cancer pain among populations of doctors in the United Kingdom have been assessed by means of a postal questionnaire. The results indicate that amongst the sample of doctors completing the questionnaire the basic principles of pain control in cancer appear to be understood. Regular oral morphine or diamorphine are most often chosen with the dose being determined mainly by the severity of pain with no arbitrary upper limit. Fears of addiction and respiratory depression, and a relatively long prognosis no longer appear to be major deterrents to the use of strong opioid analgesics. These data indicate considerable shifts in opinion in the doctors responding to the questionnaire and these results and their implications for current and future teaching about the management of cancer pain are discussed.

摘要

通过邮政问卷调查对英国医生群体中癌症疼痛患者的处方开具情况进行了评估。结果表明,在完成问卷的医生样本中,癌症疼痛控制的基本原则似乎得到了理解。最常选用的是常规口服吗啡或二醋吗啡,剂量主要由疼痛严重程度决定,没有任意上限。对成瘾和呼吸抑制的担忧以及相对较长的预后似乎不再是使用强效阿片类镇痛药的主要阻碍。这些数据表明,回复问卷的医生观点有了相当大的转变,本文将讨论这些结果及其对当前和未来癌症疼痛管理教学的影响。

相似文献

1
Analgesics in cancer pain: current practice and beliefs.癌症疼痛中的镇痛药:当前的实践与认知
Br J Cancer. 1991 Feb;63(2):271-4. doi: 10.1038/bjc.1991.63.
2
Attitudes of Swiss physicians in prescribing opiates for cancer pain.
Support Care Cancer. 1993 Sep;1(5):259-62. doi: 10.1007/BF00366046.
3
Attitudes of Italian general practitioners in the treatment of cancer pain. The Committee of the Associazione Italiana di Oncologia Medica (AIOM).
Tumori. 1997 Jul-Aug;83(4):729-31. doi: 10.1177/030089169708300402.
4
[Cancer pain management].[癌症疼痛管理]
Gan To Kagaku Ryoho. 1989 Apr;16(4 Pt 2-1):1031-7.
5
Pharmacological management of cancer pain. A guide for the health care professional.癌症疼痛的药物治疗。医护专业人员指南。
Cancer Nurs. 1992 Oct;15(5):331-46.
6
Pharmacologic management of cancer pain.癌症疼痛的药物治疗
Semin Oncol. 1994 Dec;21(6):718-39.
7
Control of pain in terminal cancer.
Br Med Bull. 1990 Jan;46(1):279-91. doi: 10.1093/oxfordjournals.bmb.a072391.
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[Patterns of prescription of opioid analgesics in Hôtel-Dieu de France of Beyrouth].[贝鲁特法国主宫医院阿片类镇痛药的处方模式]
Encephale. 2016 Dec;42(6):511-516. doi: 10.1016/j.encep.2016.05.010. Epub 2016 Oct 21.
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[Pain therapy in pediatric oncology].
Fortschr Med. 1998 May 30;116(15):31-6.
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The University of Rochester Pain Center's Second Annual Hugh Cumming Memorial Teaching Day on Cancer Pain. Oral analgesics for cancer pain: pharmacology, anatomy and physiology.罗切斯特大学疼痛中心第二届年度休·卡明纪念癌症疼痛教学日。癌症疼痛的口服镇痛药:药理学、解剖学与生理学。
Am J Hosp Palliat Care. 1991 Nov-Dec;8(6):19-26. doi: 10.1177/104990919100800609.

引用本文的文献

1
Morphinofobia: the situation among the general population and health care professionals in North-Eastern Portugal.吗啡恐惧症:葡萄牙东北部普通人群和卫生保健专业人员中的情况。
BMC Palliat Care. 2010 Jun 22;9:15. doi: 10.1186/1472-684X-9-15.
2
Attitudes of Swiss physicians in prescribing opiates for cancer pain.
Support Care Cancer. 1993 Sep;1(5):259-62. doi: 10.1007/BF00366046.
3
Treatment for cancer pain in France.法国的癌症疼痛治疗。
BMJ. 1995 Aug 5;311(7001):387. doi: 10.1136/bmj.311.7001.387.

本文引用的文献

1
Management of Intractable Pain.顽固性疼痛的管理
Proc R Soc Med. 1963 Mar;56(3):191-3. doi: 10.1177/003591576305600320.
2
Undertreatment of medical inpatients with narcotic analgesics.住院患者使用麻醉性镇痛药治疗不足。
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Relative bioavailability of controlled release morphine tablets (MST continus) in cancer patients.控释吗啡片(美施康定)在癌症患者中的相对生物利用度。
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Interpreting survival rates for the treatment of decompensated diabetes: are we saving too many lives?解读失代偿性糖尿病治疗的生存率:我们挽救的生命是否过多?
Lancet. 1987 Nov 21;2(8569):1192-5. doi: 10.1016/s0140-6736(87)91330-4.
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Controlled-release morphine (MST Contin) in advanced cancer. The European experience.控释吗啡(美施康定)用于晚期癌症。欧洲的经验。
Cancer. 1989 Jun 1;63(11 Suppl):2378-82. doi: 10.1002/1097-0142(19890601)63:11<2378::aid-cncr2820631150>3.0.co;2-8.