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新月弯孢霉甾体11β-羟化酶的诱导

Induction of steroidal 11 beta-hydroxylase of Cochliobolus lunatus.

作者信息

Zakelj-Mavric M, Belic I

机构信息

Institute of Biochemistry, Medical Faculty, E. Kardelj University, Ljubljana, Yugoslavia.

出版信息

J Steroid Biochem Mol Biol. 1991 Jan;38(1):117-8.

PMID:1997119
Abstract

The induction of steroidal 11 beta-hydroxylase of Cochliobolus lunatus was studied and the effect of the structure of steroid inducers and additives on the extent of enzyme induction determined. 21-Hydroxyprogesterone was found to be the best inducer and Torlak peptone 1 the best additive. A certain parallelism was found between the induction of 11 beta-hydroxylase of Cochliobolus lunatus and 11 alpha-hydroxylase of Rhizopus nigricans.

摘要

对新月弯孢霉甾体11β-羟化酶的诱导进行了研究，并确定了甾体诱导剂和添加剂的结构对酶诱导程度的影响。发现21-羟基孕酮是最佳诱导剂，托尔拉克蛋白胨1是最佳添加剂。在新月弯孢霉11β-羟化酶的诱导与黑根霉11α-羟化酶的诱导之间发现了一定的平行关系。

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