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[疟疾研究]

[Malaria study].

作者信息

Etter H, Koop B L, Junghanss T, Braendli B

机构信息

Poliklinik des Schweiz. Tropeninstituts, Basel.

出版信息

Schweiz Rundsch Med Prax. 1991 Jan 22;80(4):72-4.

PMID:1998082
Abstract

Compliance with malaria prophylaxis or reserve drugs was investigated in 477 individuals travelling to regions with endemic malaria. Correct intake of prophylactic medication was confirmed in 225 out of 285 (= 78%). Compliance was independent of type of drug (Mefloquine, Sulfadoxine-Pyrimethamine, Chloroquine). Two tourists missed to start prophylaxis one week before the onset of their travel. 14 travellers stopped prophylactic medication too early after their return, 31 tourists took too high doses of mefloquine. None of the tourists travelling to countries with a therapeutic reserve only became sick, whereas two travelling to Africa contracted malaria.

摘要

对477名前往疟疾流行地区旅行的人员进行了疟疾预防用药或备用药物依从性调查。在285名人员中,有225人(占78%)被证实正确服用了预防药物。依从性与药物类型(甲氟喹、磺胺多辛-乙胺嘧啶、氯喹)无关。两名游客在旅行开始前一周未开始预防用药。14名旅行者在返回后过早停止了预防用药,31名游客服用了过高剂量的甲氟喹。前往仅设有治疗储备药物国家的游客中无人患病,而前往非洲的两名游客感染了疟疾。

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