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Identification of the base substitution responsible for the Ag(x/y) polymorphism of apolipoprotein B-100.

作者信息

Wu M J, Bütler E, Bütler R, Schumaker V N

机构信息

Department of Chemistry and Biochemistry, University of California, Los Angeles 90024-1570.

出版信息

Arterioscler Thromb. 1991 Mar-Apr;11(2):379-84. doi: 10.1161/01.atv.11.2.379.

Abstract

The identification of the base substitution responsible for Ag(x/y) completes the description of the antigen group polymorphisms associated with the apolipoprotein B polypeptide. Surprisingly, all five antigen group polymorphisms alter restriction endonuclease cleavage sites and have associated restriction fragment length polymorphisms, thereby providing a convenient alternative for antigen group phenotyping.

摘要

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