Department of Orthopedics, Gävle Hospital and Center for Research and Development, Uppsala University/County Council of Gävleborg, Gävle, Sweden.
Acta Orthop. 2009 Dec;80(6):670-4. doi: 10.3109/17453670903278258.
One of the main concerns regarding resurfacing arthroplasty is the viability of the remaining part of the femoral head, and the postoperative risk of a femoral neck fracture or collapse. In contrast to radiographic methods, positron emission tomography using the radiotracer [18F]-fluoride (Fluoride-PET) enables us to visualize the viability of bone in the remaining part of the head, despite the presence of the covering metal component.
This is preliminary prospective study of 14 patients who underwent an ASR resurfacing arthroplasty. Apart from clinical and radiographic analyses, all patients were analyzed by PET scan 1 week, 4 months, and 1 year after surgery.
1 patient had a minor region of osteonecrosis on PET scan at 1 week and at 4 months. After 1 year, the necrosis had increased to include most of the head. 2 other patients, normal at 4 months, had developed equally large osteonecrosis at 1 year. A fourth patient had a minor osteonecrosis at 1 year. None of the patients had clinical symptoms, and the necrotic areas were not visible on plain radiographs.
We found Fluoride PET to be a sensitive and useful method for evaluation of bone metabolism at resurfacing arthroplasty. 3 of the 14 patients had developed osteonecrosis, involving most of the head at 1 year. The late onset of the phenomenon does not support the hypothesis of surgically damaged vascularity. The presence of this complication together with the lack of visibility on plain radiographs gives reason for concern.
对于表面置换关节成形术,主要关注的问题之一是股骨头残留部分的活力,以及术后股骨颈骨折或塌陷的风险。与放射学方法相比,使用放射性示踪剂 [18F]-氟化物(氟化物-PET)的正电子发射断层扫描使我们能够在存在覆盖金属部件的情况下,观察到头残留部分的骨活力。
这是对 14 例接受 ASR 表面置换关节成形术的患者进行的初步前瞻性研究。除了临床和放射学分析外,所有患者在手术后 1 周、4 个月和 1 年均进行了 PET 扫描分析。
1 例患者在术后 1 周和 4 个月时 PET 扫描显示有小区域骨坏死。1 年后,坏死已扩大至包括大部分头部。另外 2 例患者在 4 个月时正常,在 1 年时出现了同样大的骨坏死。第 4 例患者在 1 年时出现了小面积骨坏死。所有患者均无临床症状,且坏死区域在普通 X 光片上不可见。
我们发现氟化物 PET 是评估表面置换关节成形术中骨代谢的一种敏感且有用的方法。14 例患者中有 3 例在 1 年内发生了骨坏死,累及大部分头部。该现象的迟发不支持手术损伤血管的假说。这种并发症的存在以及普通 X 光片上的不可见性令人担忧。