Porter School of Environmental Studies, Department of Zoology, Tel Aviv University, Ramat Aviv, Israel.
BMC Genet. 2009 Dec 8;10:80. doi: 10.1186/1471-2156-10-80.
Genetic studies have often produced conflicting results on the question of whether distant Jewish populations in different geographic locations share greater genetic similarity to each other or instead, to nearby non-Jewish populations. We perform a genome-wide population-genetic study of Jewish populations, analyzing 678 autosomal microsatellite loci in 78 individuals from four Jewish groups together with similar data on 321 individuals from 12 non-Jewish Middle Eastern and European populations.
We find that the Jewish populations show a high level of genetic similarity to each other, clustering together in several types of analysis of population structure. Further, Bayesian clustering, neighbor-joining trees, and multidimensional scaling place the Jewish populations as intermediate between the non-Jewish Middle Eastern and European populations.
These results support the view that the Jewish populations largely share a common Middle Eastern ancestry and that over their history they have undergone varying degrees of admixture with non-Jewish populations of European descent.
关于地理位置相距甚远的犹太人群体彼此之间的遗传相似度更高，还是与临近的非犹太人群体之间的遗传相似度更高，遗传研究经常得出相互矛盾的结果。我们对犹太人群体进行了全基因组群体遗传学研究，分析了来自四个犹太群体的 78 个人的 678 个常染色体微卫星位点，以及来自 12 个非犹太中东和欧洲人群的 321 个人的类似数据。
我们发现，犹太人群体彼此之间具有高度的遗传相似性，在几种群体结构分析中聚类在一起。此外，贝叶斯聚类、邻接法树和多维标度将犹太人群体置于非犹太中东和欧洲人群之间的中间位置。
这些结果支持这样一种观点，即犹太人群体在很大程度上共享一个中东共同祖先，并且在其历史上，他们与具有欧洲血统的非犹太人群体经历了不同程度的混合。
