Department of Women's Anaesthesia, Women's and Children's Hospital, North Adelaide, SA 5006, Australia.
Anesth Analg. 2010 Feb 1;110(2):601-2. doi: 10.1213/ANE.0b013e3181c8a6e0. Epub 2009 Dec 8.
We report a case of a final-year anesthesiology trainee who developed a severe allergic reaction to cutaneous exposure of succinylcholine. Intradermal testing was strongly positive to succinylcholine and all the aminosteroid neuromuscular blocking drugs (NMBDs). Specific immunoglobulin E to succinylcholine was also strongly positive. This unusual case of an anesthesiologist acquiring an allergy to an NMBD through occupational exposure has a significant effect on his practice of anesthesia. However, by avoiding operating rooms with a high usage of NMBDs and by wearing personal protective equipment, the anesthesiologist has worked in clinical anesthesia without incident.
我们报告了一例在最后一年接受麻醉学培训的学员,他在接触琥珀胆碱时发生严重过敏反应。皮内试验对琥珀胆碱和所有氨基甾体类神经肌肉阻滞剂(NMBDs)均呈强阳性。对琥珀胆碱的特异性免疫球蛋白 E 也呈强阳性。这种通过职业接触使麻醉师对 NMBD 产生过敏的不常见情况对他的麻醉实践有重大影响。然而,通过避免使用 NMBDs 高的手术室,并佩戴个人防护设备,该麻醉师在临床麻醉工作中未发生意外。