Flow Inc., Portland, Oregon 97239, USA.
Am J Trop Med Hyg. 2009 Dec;81(6):921-6. doi: 10.4269/ajtmh.2009.09-0202.
Great advances have been made in developing rapid diagnostic tests (RDTs) for diagnosing malaria. To date, RDTs present an exceedingly practical format for malaria diagnosis that outperforms traditional microscopy and more experimental next generation devices in the development pipeline. However, although use of such tests is accepted in principle, their actual use has lagged. Furthermore, study of how these tests perform, what their limitations are, and how to work with these limitations to still use them effectively has stagnated. We propose that the study and implementation of such RDTs should be aggressively advanced and propose a series of questions that can guide efforts.
在开发用于诊断疟疾的快速诊断检测(RDT)方面已经取得了重大进展。迄今为止,RDT 为疟疾诊断提供了一种极其实用的方法,在性能上优于传统显微镜和开发管道中的更具实验性的下一代设备。然而,尽管这些测试的使用在原则上是被接受的,但实际上它们的使用却滞后了。此外,对这些测试的性能、局限性以及如何克服这些局限性以仍然有效地使用它们的研究也停滞不前。我们建议积极推进对这些 RDT 的研究和实施,并提出一系列可以指导工作的问题。