Maglakelidze G M
Georgian Med News. 2009 Nov(176):21-6.
The current literature on mechanisms involved in the pathogenesis of prostatitis/chronic pelvic pain syndrome (CPPS) is reviewed. Based on the literature and own observation it is suggested that, in the pathogenesis of chronic prostatitis are involved several mechanisms, and the mechanism of infection, especially in the later stages of the disease, is not determinative. Author gives his views concerning the chronic prostatitis. He suggests that the disease is laid down by virus (or group of viruses) which exists in the cell during embryonic life. Lifelong effect of virus (or group of viruses) on cells may initiate different chronic inflammatory processes and different pathologic changes in the organism, including prostatitis. Analysis of the literature showed a lack of a complete understanding of the causes and mechanisms of chronic prostatitis, but it also showed that the prostatitis syndrome is no longer a faceless myth. It is a reality, and the new awareness of its importance may give new hope for patients suffering from this intractable pain syndrome Further research in this area will help to better understand the nature of chronic prostatitis and find the best possible solutions in its treatment.
本文综述了目前关于前列腺炎/慢性盆腔疼痛综合征（CPPS）发病机制的文献。基于文献及自身观察，提示慢性前列腺炎的发病涉及多种机制，而感染机制，尤其是在疾病后期，并非决定性因素。作者阐述了其对慢性前列腺炎的观点。他认为该疾病由胚胎期存在于细胞内的病毒（或一组病毒）引发。病毒（或一组病毒）对细胞的终身影响可能引发机体不同的慢性炎症过程和不同的病理变化，包括前列腺炎。对文献的分析表明，人们对慢性前列腺炎的病因和机制缺乏全面理解，但也显示出前列腺炎综合征不再是一个模糊的谜团。它是一个现实问题，对其重要性的新认识可能为患有这种顽固性疼痛综合征的患者带来新希望。该领域的进一步研究将有助于更好地理解慢性前列腺炎的本质，并找到最佳治疗方案。
