Kuethe Maarten C, Vaessen-Verberne Anja A, Bindels Patrick J, van Aalderen Wim M
Department of Paediatrics, Amphia Hospital, Breda, Noord Brabant, Netherlands.
Prim Care Respir J. 2010 Mar;19(1):62-7, 8p following 67. doi: 10.4104/pcrj.2009.00063.
To investigate whether there are differences in asthma characteristics between two populations of children with moderate asthma requiring inhaled corticosteroids (ICS) who are treated in general practice or in hospital practice.
45 children from general practice and 62 from hospital practice, diagnosed with asthma and treated with ICS, were analysed in terms of lung function parameters, asthma control (ACQ), and use of medication.
Children in general practice did not differ significantly from those in paediatric practice with respect to mean age, lung function tests, and corrected daily dose of ICS. The median ACQ score was higher (representing poorer control) in the general practice group than in the paediatric practice group (0.67 and 0.33 respectively, p < 0.05). Fewer children (22.7%) from the general practice group than from the paediatric group (98.4%) had planned review visits (p< 0.01). Prescriptions for a combination ICS/long-acting beta2-agonist (LABA) inhaler were 28.9% in the general practice group and 6.5% in the paediatric group (p<0.05).
The hospital-based group was better controlled with less frequent use of combination therapy. Our observations stress the necessity for regular review visits for children with moderately severe asthma especially in general practice.
研究在接受吸入性糖皮质激素(ICS)治疗的中度哮喘儿童中,在全科医疗或医院医疗环境下接受治疗的两组儿童的哮喘特征是否存在差异。
分析了45名来自全科医疗的儿童和62名来自医院医疗的儿童,这些儿童均被诊断为哮喘并接受ICS治疗,分析内容包括肺功能参数、哮喘控制情况(ACQ)以及药物使用情况。
在平均年龄、肺功能测试以及ICS的校正日剂量方面,全科医疗组的儿童与儿科医疗组的儿童没有显著差异。全科医疗组的ACQ评分中位数更高(代表控制较差),高于儿科医疗组(分别为0.67和0.33,p<0.05)。与儿科医疗组(98.4%)相比,全科医疗组中计划复诊的儿童较少(22.7%)(p<0.01)。在全科医疗组中,ICS/长效β2受体激动剂(LABA)联合吸入器的处方率为28.9%,而在儿科医疗组中为6.5%(p<0.05)。
以医院为基础的组哮喘控制更好,联合治疗使用频率更低。我们的观察结果强调了对中度至重度哮喘儿童进行定期复诊的必要性,尤其是在全科医疗环境中。