Mwambete Kennedy D
Pharmaceutical Microbiology, School of Pharmacy, MIUHAS, Dar es Salaam, Tanzania.
East Afr J Public Health. 2009 Aug;6(2):200-4. doi: 10.4314/eajph.v6i2.51774.
To assess the prevalence of antibiotic misuse among boarding secondary school students in Dares Salaam.
This descriptive cross-sectional study was conducted over 3-month period amongst boarding secondary school students. A randomized sample of students was recruited from at least 3 secondary schools from each of the three municipalities of Dar es Salaam region. Questionnaire with both closed-and open-ended questions was used for data collection in which socio-demographic characteristics, knowledge of ATBs, sources of prescription, procurement of ATBs, infections for which ATBs were used, and antibiotic therapy compliance were assessed. The collected data were analyzed using SPSS/PC+ version 15.0 computer package.
A total of 424 randomly selected students with a mean age of 20 years were interviewed, of those 150 were females and 274 were males. Majority of the respondents (74%) have had heard of ATBs, however only 105 (25%) respondent described them correctly. Prevalence of antibiotic usage among the students was high (69%). Of 293 students who have had used ATBs, 73% of them had procured the drugs on prescription; 170 (58%) respondents used the ATBs for non-microbial infections/diseases, only 183 (62%) were compliant to antibiotic therapies (ABT), while 226 (77%) admitted to have had shared ATBs with friends/relatives whenever deemed necessary. Of those who had procured ATBs without prescriptions, 66% of them obtained the drugs from pharmacies.
The study revealed inadequate knowledge on ATBs among the respondents and that pharmacies played a major role on easy availability of ATBs as over-the-counter (OTC) drugs attributing to high rate of irrational use of ATBs. We recommended that health care providers should succinctly explain to patients the importance of ABT compliance and adverse effects of non-compliance. Regulatory authorities should re-enforce the laws on sales of ATBs by prohibiting their availability as OTC drugs.
评估达累斯萨拉姆寄宿制中学生中抗生素滥用的流行情况。
本描述性横断面研究在寄宿制中学生中进行,为期3个月。从达累斯萨拉姆地区三个市的至少3所中学中随机抽取学生样本。使用包含封闭式和开放式问题的问卷进行数据收集,评估社会人口统计学特征、对抗生素的了解、处方来源、抗生素采购、使用抗生素治疗的感染情况以及抗生素治疗依从性。使用SPSS/PC + 15.0版计算机软件包对收集的数据进行分析。
共采访了424名随机抽取的学生,平均年龄为20岁,其中150名是女生,274名是男生。大多数受访者(74%)听说过抗生素,但只有105名(25%)受访者能正确描述它们。学生中抗生素使用的流行率很高(69%)。在293名使用过抗生素的学生中,73%是凭处方购买药物;170名(58%)受访者将抗生素用于非微生物感染/疾病,只有183名(62%)依从抗生素治疗,而226名(77%)承认在必要时会与朋友/亲属分享抗生素。在那些无处方购买抗生素的人中,66%是从药店获取药物。
研究表明受访者对抗生素的了解不足,且药店在抗生素作为非处方药容易获取方面起了主要作用,这导致了抗生素的高不合理使用率。我们建议医疗保健提供者应向患者简明解释抗生素治疗依从性的重要性以及不依从的不良反应。监管当局应加强关于抗生素销售的法律,禁止其作为非处方药出售。