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发展中国家的抗逆转录病毒药物配给方案:一篇关于与抗逆转录病毒药物项目成败相关的策略和伦理问题的综述文章。

Anti-retroviral (ARV) rationing schemes in developing countries: a review article on strategies and ethical issues related to the successes and failures of ARV programmes.

作者信息

Nsimba Stephen E D

机构信息

Department of Clinical Pharmacology, School of Medicine, Muhimbili University of Health & Allied Sciences, Dar-es-Salaam, Tanzania.

出版信息

East Afr J Public Health. 2009 Aug;6(2):219-22. doi: 10.4314/eajph.v6i2.51788.

Abstract

When a patient receives a counterfeit drug, he/she becomes a victim of fraud medicine and is put at risk of developing adverse effects from unwanted medication that is not prescribed. These individuals health also becomes compromised because they are cheated of both successful treatment regimens and economically. Indeed counterfeit drugs pose many threats to society; not only to the individual in terms of the health side effects experienced, but also to the public in terms of trade relations, economic implications, and the effects on global pandemics. Apart from the pharmaceutical aspect in producing substandard drugs, there area also climatic or environmental factors as well as patients and economic factors. All these need to be addressed when considering any proper rationing strategy for antiretroviral drugs (ARVs) in sub-Saharan countries. Short of that, there is a great danger that the shelf life of ARV will be soon lost and once resistance comes in we will be in big problems.

摘要

当患者使用假药时,他/她就成了假药欺诈的受害者,面临着因未按处方使用的有害药物而产生不良反应的风险。这些人的健康也会受到损害,因为他们在成功的治疗方案和经济方面都受到了欺骗。事实上,假药对社会构成了许多威胁;不仅对个人会产生健康副作用,而且对公众在贸易关系、经济影响以及对全球大流行病的影响方面都会造成威胁。除了生产不合格药品的制药方面因素外,还有气候或环境因素以及患者和经济因素。在考虑撒哈拉以南非洲国家抗逆转录病毒药物(ARV)的任何合理配给策略时,所有这些都需要得到解决。否则,存在很大的风险,即抗逆转录病毒药物的保质期很快就会丧失,一旦产生耐药性,我们将面临大问题。

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