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[Age and changes in the activity of several energy metabolism enzymes in the rabbit aorta].

作者信息

Mikhaĭlova I A, Nadirova T Ia

出版信息

Vopr Med Khim. 1977 Jul-Aug;23(4):463-8.

PMID:200002
Abstract

Age alterations in the activity of several key enzymes of glucose oxidative breakdown (hexokinase, glucose-6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase and cytochrome c oxidase) were studied in extracts from rabbit aorta. The hexokinase activity was measured also in mitochondrial fraction. The activity of all the enzymes studied in rabbit aorta (calculated either per 1 g of the tissue or per 1 mg of proteins) was the highest at the age from 1-2 weeks to 1 month. The minimal activity was observed in adult animals, which were 1-2 years old, In aorta of 3,5-4 years old rabbits an increase (per 1 g of the tissue) in the activity of the enzymes was observed.

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