[部分交感神经切除术后肝脏能量代谢某些酶活性变化的性质]

[Nature of changes in the activity of certain enzymes of energy metabolism in the liver after partial sympathectomy].

作者信息

Parfenova N S, Shanygina K I

出版信息

Vopr Med Khim. 1976 Nov-Dec;22(6):808-12.

Abstract

Partial sympathectomy of rat liver, carried out by bilateral section of celiac nerves, caused a distinct increase in the activity of hexokinase and glucose-6-phosphate dehydrogenase and (less distinctly) of 6-phosphogluconate dehydrogenase and lactate dehydrogenase in liver tissue. The alterations in glucokinase activity were not statistically significant. Noradrenaline disappeared completely from rat liver after the celiac nerves section. Activities of the above-mentioned enzymes were altered to the same degree in sympathectomized liver of adrenalectomized animals. The increase in the hexokinase and glucose-6-phosphate dehydrogenase activity was prevented by administration of actinomycin D immediately after the section of celiac nerves. The data obtained suggest that after section of liver celiac nerves the alterations in the enzymatic activities are determined by the increase of their biosynthesis and occur as a result of impairment of liver sympathetic innervation.

摘要

通过双侧切断腹腔神经对大鼠肝脏进行部分交感神经切除术，导致肝脏组织中己糖激酶和葡萄糖-6-磷酸脱氢酶的活性明显增加，6-磷酸葡萄糖酸脱氢酶和乳酸脱氢酶的活性增加则不太明显。葡萄糖激酶活性的改变无统计学意义。切断腹腔神经后，去甲肾上腺素从大鼠肝脏中完全消失。在肾上腺切除动物的交感神经切除肝脏中，上述酶的活性改变程度相同。在切断腹腔神经后立即给予放线菌素D可阻止己糖激酶和葡萄糖-6-磷酸脱氢酶活性的增加。所获得的数据表明，切断肝脏腹腔神经后，酶活性的改变是由其生物合成增加所决定的，并且是肝脏交感神经支配受损的结果。

相似文献

1

[Nature of changes in the activity of certain enzymes of energy metabolism in the liver after partial sympathectomy].[部分交感神经切除术后肝脏能量代谢某些酶活性变化的性质]

Vopr Med Khim. 1976 Nov-Dec;22(6):808-12.

2

[Effect of bilateral subdiaphragmatic vagotomy on the activity of several energy metabolism enzymes in the liver].

Biull Eksp Biol Med. 1976 Jul;82(7):814-5.

3

[Participation of the hypothalamus in regulating the activity of rat liver energy metabolism enzymes].

Zh Evol Biokhim Fiziol. 1976 Sep-Oct;12(5):405-10.

4

[Activity of energy metabolism related enzymes in the myocardium and liver following administration of large doses of noradrenaline].[大剂量去甲肾上腺素给药后心肌和肝脏中能量代谢相关酶的活性]

Biull Eksp Biol Med. 1975 Dec;80(12):23-5.

5

[Activity of hexokinase, glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase in intact and sympathectomized rat testes exposed to hormones].[暴露于激素下的完整及交感神经切除大鼠睾丸中己糖激酶、葡萄糖-6-磷酸脱氢酶和6-磷酸葡萄糖酸脱氢酶的活性]

Vopr Med Khim. 1973;19(6):582-6.

6

The effects of n-3 polyunsaturated fatty acids by gavage on some metabolic enzymes of rat liver.经口灌胃给予n-3多不饱和脂肪酸对大鼠肝脏某些代谢酶的影响。

Prostaglandins Leukot Essent Fatty Acids. 2004 Aug;71(2):131-5. doi: 10.1016/j.plefa.2004.03.002.

7

[Enzymatic activity of glucose-6-phosphate metabolism in the liver during the administration of a hepatic carcinogen].[给予肝脏致癌物期间肝脏中葡萄糖-6-磷酸代谢的酶活性]

Vopr Med Khim. 1976 Jul-Aug;22(4):551-5.

8

[Activity of hexokinase and dehydrogenases of the pentose phosphate pathway in sympathectomized rat testes].[去交感神经大鼠睾丸中己糖激酶和磷酸戊糖途径脱氢酶的活性]

Zh Evol Biokhim Fiziol. 1973 Jan-Feb;9(1):51-5.

9

[Effect of sectioning the celiac and vagus nerves on the activity and isoenzymatic composition of rat liver lactate dehydrogenase].[切断腹腔神经和迷走神经对大鼠肝脏乳酸脱氢酶活性及同工酶组成的影响]

Vopr Med Khim. 1977 Sep-Oct;23(5):650-2.

10

[Study of the mechanism of erythropoietin effect on energy metabolism in the bone marrow].[促红细胞生成素对骨髓能量代谢影响机制的研究]

Vopr Med Khim. 1976 Jan-Feb;22(1):14-6.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

文档翻译

学术文献翻译模型，支持多种主流文档格式。