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创伤性脑损伤与嗅觉缺陷:两种嗅觉测试的故事!

Traumatic brain injury and olfactory deficits: the tale of two smell tests!

作者信息

Fortin Audrey, Lefebvre Mathilde Beaulieu, Ptito Maurice

机构信息

Centre de réadaptation Lucie Bruneau, Montréal, Canada.

出版信息

Brain Inj. 2010 Jan;24(1):27-33. doi: 10.3109/02699050903446815.

DOI:10.3109/02699050903446815
PMID:20001480
Abstract

PRIMARY OBJECTIVE

Olfactory functions are not systematically evaluated following traumatic brain injury (TBI). This study aimed at comparing two smell tests that are used in a clinical setting.

RESEARCH DESIGN

The University of Pennsylvania Smell Identification Test (UPSIT) and the Alberta Smell Test were compared in terms of assessment time, cost and diagnosis. Parameters associated with olfactory loss such as injury severity, type of cerebral lesion and depressive data were considered. Forty-nine TBI patients admitted to an outpatient rehabilitation programme took part in this experiment.

RESULTS

The scores of the two smell tests were significantly correlated. Both tests indicated that patients with frontal lesion performed significantly worse than patients with other types of lesion. Mood and injury severity were not associated with olfactory impairment when age was taken into account. Between 40-44% of the patients showing olfactory impairments were not aware of their deficit.

CONCLUSIONS

Since a significant proportion of the patients showing olfactory impairments were not aware of their deficit, it is recommended than clinicians systematically evaluate olfactory functions using the Alberta Smell test. To refine their diagnosis, the UPSIT can also be used.

摘要

主要目的

创伤性脑损伤(TBI)后嗅觉功能未得到系统评估。本研究旨在比较临床中使用的两种嗅觉测试。

研究设计

对宾夕法尼亚大学嗅觉识别测试(UPSIT)和艾伯塔嗅觉测试在评估时间、成本和诊断方面进行比较。考虑了与嗅觉丧失相关的参数,如损伤严重程度、脑损伤类型和抑郁数据。49名参加门诊康复项目的TBI患者参与了本实验。

结果

两种嗅觉测试的分数显著相关。两项测试均表明,额叶损伤患者的表现明显比其他类型损伤患者差。考虑年龄因素时,情绪和损伤严重程度与嗅觉障碍无关。40 - 44%的嗅觉受损患者未意识到自己的缺陷。

结论

由于相当一部分嗅觉受损患者未意识到自己的缺陷,建议临床医生使用艾伯塔嗅觉测试系统评估嗅觉功能。为了完善诊断,也可使用UPSIT。

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