Thoracic Surgery Service, Hospital Universitario Mutua de Terrassa, 08221 Terrassa, Barcelona, Spain.
Future Oncol. 2009 Dec;5(10):1545-53. doi: 10.2217/fon.09.131.
The tumor, node and metastasis classification of malignant tumors is periodically revised. Its seventh edition includes the updated classification for lung cancer, based on the analyses of the International Association for the Study of Lung Cancer international database. It is the largest validation ever carried out to date: 100,869 patients registered in 46 databases from 20 countries. The analysis of this database allowed a detailed study of the impact of tumor size on prognosis, the reclassification of additional tumor nodules, the reclassification of pleural dissemination and the separation of two groups of metastatic disease. These changes led to modifications in stage grouping that better differentiate tumors with different prognosis. This updated classification is also recommended for small-cell lung cancer, and for broncho-pulmonary carcinoids. A new international nodal map with stations and zones, and a histological definition of visceral pleura invasion, have also been proposed.
肿瘤、淋巴结和转移（TNM）分类系统定期修订。其第七版纳入了基于国际肺癌研究协会（IASLC）国际数据库分析的肺癌更新分类。这是迄今为止最大规模的验证：来自 20 个国家的 46 个数据库共登记了 100869 例患者。该数据库分析使我们能够详细研究肿瘤大小对预后的影响、附加肿瘤结节的重新分类、胸膜播散的重新分类以及转移疾病的两个亚组的分离。这些变化导致了分期分组的修改，从而更好地区分具有不同预后的肿瘤。该更新的分类也推荐用于小细胞肺癌和支气管肺类癌。还提出了新的国际淋巴结图，包括淋巴结站和区，以及内脏胸膜侵犯的组织学定义。
