Bandini L G, Schoeller D A, Fukagawa N K, Wykes L J, Dietz W H
Clinical Research Center, Massachusetts Institute of Technology, Cambridge 02139.
Pediatr Res. 1991 Jan;29(1):70-7. doi: 10.1203/00006450-199101000-00014.
We measured body composition, resting metabolic rate (RMR), and total energy expenditure (TEE) in a group of adolescents with cerebral palsy (CP) and myelodysplasia (M) aged 13- to 20-y-old using indirect calorimetry and the doubly labeled water method. Fat-free mass (FFM), RMR, and TEE were significantly lower in both the CP and M groups than comparable measurements in a control group of normal adolescent males and females. The ratio of TEE to RMR did not differ between controls and ambulatory M and CP subjects. However, TEE/RMR was significantly lower in the nonambulatory M and CP subjects than in controls (p less than 0.01). Our data indicate that energy requirements are reduced in both populations because both FFM and activity are decreased. Although energy requirements were decreased in both groups, the relationships between FFM and body weight differed. FFM and body weight were significantly correlated with RMR only in the M group. These data suggest that the type of paralysis in a handicapped population may affect resting energy expenditure.
我们使用间接测热法和双标记水法，对一组年龄在13至20岁的患有脑瘫（CP）和脊髓发育不良（M）的青少年进行了身体成分、静息代谢率（RMR）和总能量消耗（TEE）的测量。CP组和M组的去脂体重（FFM）、RMR和TEE均显著低于正常青少年男性和女性对照组的相应测量值。对照组与可行走的M组和CP组受试者之间的TEE与RMR之比没有差异。然而，非行走的M组和CP组受试者的TEE/RMR显著低于对照组（p<0.01）。我们的数据表明，这两个人群的能量需求均降低，因为FFM和活动量都减少了。虽然两组的能量需求都降低了，但FFM与体重之间的关系有所不同。仅在M组中，FFM和体重与RMR显著相关。这些数据表明，残疾人群体中的瘫痪类型可能会影响静息能量消耗。
