Johnson R K, Goran M I, Ferrara M S, Poehlman E T
Department of Nutritional Sciences, University of Vermont, Burlington 05405, USA.
J Am Diet Assoc. 1996 Feb;96(2):145-8. doi: 10.1016/S0002-8223(96)00043-0.
To determine whether resting metabolic rate (RMR) is higher or lower in adults with cerebral palsy compared with the RMR of control subjects and to further examine physical characteristics of cerebral palsy that might affect RMR.
Twenty-one adults with cerebral palsy (9 women, 12 men) were compared with 50 control subjects (25 men, 25 women) within the same age range (18 through 50 years). The following measurements were made: RMR by indirect calorimetry, anthropometrics, body composition, and habitual physical activity patterns. The study was conducted at the University of Vermont General Clinical Research Center and the Ball State University Human Performance Laboratory.
Mean values +/- standard deviations, t tests, Pearson product-moment correlation coefficients, analysis of covariance, and stepwise multiple correlation regression analysis were used to examine the relationships among variables of interest.
No significant differences were found in body weight, body mass index, fat mass, percentage body fat, and measured RMR between the two groups. The subjects with cerebral palsy were significantly shorter, had less fat-free mass, and expended fewer kilocalories in leisure time activities than the control subjects. After statistical adjustment for differences in fat-free mass, the subjects with cerebral palsy had a 14% (P < .001) higher adjusted RMR (1,742 kcal/day) compared with that of the control subjects (1,534 kcal/day). According to stepwise regression analysis, RMR was best predicted in the entire sample by fat-free mass and the presence or absence of athetosis (multiple R = .83, P < .001). The presence of cerebral palsy alone was not significantly correlated with RMR.
The increased energy requirements of adults with cerebral palsy can be partially explained by athetotic movements. In this sample, the presence of athetosis increased RMR by an average of 524 kcal/day.
确定与对照组相比，脑瘫成人的静息代谢率（RMR）是更高还是更低，并进一步研究可能影响RMR的脑瘫身体特征。
将21名脑瘫成人（9名女性，12名男性）与50名年龄范围相同（18至50岁）的对照组（25名男性，25名女性）进行比较。进行了以下测量：通过间接测热法测量RMR、人体测量学、身体成分和习惯性身体活动模式。该研究在佛蒙特大学综合临床研究中心和鲍尔州立大学人体性能实验室进行。
使用平均值±标准差、t检验、Pearson积矩相关系数、协方差分析和逐步多元相关回归分析来研究感兴趣变量之间的关系。
两组在体重、体重指数、脂肪量、体脂百分比和测得的RMR方面均未发现显著差异。与对照组相比，脑瘫患者明显更矮，去脂体重更少，休闲活动中消耗的千卡热量更少。在对去脂体重差异进行统计调整后，脑瘫患者的调整后RMR（1,742千卡/天）比对照组（1,534千卡/天）高14%（P <.001）。根据逐步回归分析，在整个样本中，去脂体重和是否存在手足徐动症对RMR的预测效果最佳（复相关系数R =.83，P <.001）。仅脑瘫的存在与RMR无显著相关性。
脑瘫成人增加的能量需求可部分由手足徐动症运动来解释。在本样本中，手足徐动症的存在使RMR平均增加524千卡/天。
