Kuppahally Suman S, Foster Elyse, Shoor Stanford, Steimle Anthony E
Division of Cardiology, University of Utah, 50 North Medical Drive, Salt Lake City, UT, 84132, USA.
Int Arch Med. 2009 Dec 12;2:39. doi: 10.1186/1755-7682-2-39.
Initial success of electrical cardioversion (ECV) of atrial fibrillation (AF) has been reported in several studies as 50%-90%, of which only 50% patients remain in sinus rhythm (SR) at the end of one year. We conducted this study to see if outcomes of other trials are applicable in managed care setting.
We conducted a retrospective study in 370 consecutive patients who underwent ECV for AF. They were reviewed for initial outcome of ECV and recurrence of AF after a successful ECV, with and without prophylactic antiarrhythmic drugs.
Initial success of ECV for AF was 65.7%. At one year, 47% remained in SR. AF for </= 3 months (p = 0.006) and pretreatment with antiarrhythmic drugs (p = 0.032) resulted in improved success. Predictors of recurrence were patients </= 65 years (p = 0.019), paroxysmal atrial fibrillation (PAF) (p = 0.0094) and alcohol consumption (p = 0.0074).
Shorter duration of AF, prophylactic antiarrhythmic drugs and serial ECVs improve outcome of ECV in AF. For younger patients with PAF and alcohol consumption, due to higher recurrence of AF, rate control or ablative therapy may be the preferred strategy.
多项研究报告称,心房颤动(AF)患者接受心脏电复律(ECV)的初始成功率为50%-90%,其中只有50%的患者在一年后仍维持窦性心律(SR)。我们开展这项研究以观察其他试验的结果是否适用于管理式医疗环境。
我们对370例连续接受AF患者进行了ECV的患者进行了一项回顾性研究。对他们进行了ECV的初始结果以及成功进行ECV后AF复发情况的评估,评估时考虑了是否使用预防性抗心律失常药物。
AF患者接受ECV的初始成功率为65.7%。一年后,47%的患者维持SR。房颤持续时间≤3个月(p = 0.006)以及使用抗心律失常药物进行预处理(p = 0.032)可提高成功率。复发的预测因素为年龄≤65岁的患者(p = 0.019)、阵发性心房颤动(PAF)(p = 0.0094)和饮酒(p = 0.0074)。
AF持续时间较短、预防性使用抗心律失常药物以及进行系列ECV可改善AF患者ECV的结果。对于患有PAF且饮酒的年轻患者,由于AF复发率较高,控制心率或消融治疗可能是首选策略。