Department of Mental Health and Behavioral Sciences, James A. Haley VA, Tampa, Florida 33612, USA.
J Int Neuropsychol Soc. 2010 Mar;16(2):262-7. doi: 10.1017/S1355617709991287. Epub 2009 Dec 11.
Debate continues about the long-term neuropsychological impact of multiple mild traumatic brain injuries (MTBI). A meta-analysis of the relevant literature was conducted to determine the impact of having a history of more than one self-reported MTBI (versus just one MTBI) across seven cognitive domains, as well as symptom complaints. The analysis was based on 8 studies, all conducted with athletes, involving 614 cases of multiple MTBI and 926 control cases of a single MTBI. The overall effect of multiple MTBI on neuropsychological functioning was minimal and not significant (d = 0.06). However, follow-up analyses revealed that multiple self-reported MTBI was associated with poorer performance on measures of delayed memory and executive functioning. The implications and limitations of these findings are discussed.
关于多次轻度创伤性脑损伤（MTBI）的长期神经心理学影响仍存在争议。对相关文献进行了荟萃分析，以确定有多次自我报告的 MTBI（而不是一次 MTBI）病史在七个认知领域以及症状抱怨方面的影响。该分析基于 8 项研究，均在运动员中进行，涉及 614 例多次 MTBI 和 926 例单次 MTBI 的对照病例。多次 MTBI 对神经心理学功能的总体影响很小且不显著（d = 0.06）。然而，后续分析显示，多次自我报告的 MTBI 与延迟记忆和执行功能测量结果较差有关。讨论了这些发现的意义和局限性。
