Dolman Kayla E, Staines Rowan S, Mughal Simran, Brown Kate E, Meehan Sean K, Staines W Richard
Department of Kinesiology and Health Sciences, University of Waterloo, 200 University Ave. W, Waterloo, ON, N2L 3G1, Canada.
Exp Brain Res. 2024 Dec 20;243(1):30. doi: 10.1007/s00221-024-06981-x.
The current work aimed to understand the behavioral manifestations that result from disruptions to the selective facilitation of task-relevant sensory information at early cortical processing stages in those with a history of concussion. A total of 40 participants were recruited to participate in this study, with 25 in the concussion history group (Hx) and 15 in the control group (No-Hx). Somatosensory-evoked potentials (SEPs) were elicited via median nerve stimulation while subjects performed a task that manipulated their focus of attention toward or away from proprioceptive cues. Participants also completed an implicit motor sequence learning task relying solely on proprioceptive cues, as well as a visual attentional blink (AB) task to understand the effect of concussion on rapid shifts in attention. The Hx SEP data replicated past work showing an absence of relevancy-based facilitation at early cortical processing stages (N20-P27) that emerged at later processing stages. Our Hx showed evidence of relevancy-based facilitation at either the P50-N70 or the N70-P100. Performance on the learning task was not significantly different between the Hx and No-Hx. Performance on the AB task revealed greater AB magnitude in the Hx compared to the No-Hx. Collectively, these results suggest a compensatory strategy in the Hx that enables them to learn to the same degree as controls. However, when the attentional system is taxed with high temporal demands there are decrements in performance. These results are of particular importance given that these individuals are at an increased risk of sustaining subsequent concussions, and musculoskeletal injuries.
当前的研究旨在了解在有脑震荡病史的个体中，早期皮层处理阶段与任务相关的感觉信息选择性促进过程受到干扰后所产生的行为表现。总共招募了40名参与者参与本研究，其中25名属于脑震荡病史组（Hx），15名属于对照组（无Hx）。在受试者执行一项操纵其对本体感觉线索的注意力焦点（朝向或远离）的任务时，通过正中神经刺激诱发体感诱发电位（SEP）。参与者还完成了一项仅依赖本体感觉线索的内隐运动序列学习任务，以及一项视觉注意瞬脱（AB）任务，以了解脑震荡对注意力快速转移的影响。Hx组的SEP数据重复了过去的研究结果，即在早期皮层处理阶段（N20 - P27）不存在基于相关性的促进作用，而这种促进作用出现在后期处理阶段。我们的Hx组在P50 - N70或N70 - P100阶段显示出基于相关性的促进作用证据。Hx组和无Hx组在学习任务上的表现没有显著差异。AB任务的表现显示，与无Hx组相比，Hx组的AB幅度更大。总体而言，这些结果表明Hx组存在一种补偿策略，使他们能够与对照组达到相同程度的学习效果。然而，当注意力系统面临高时间要求时，表现会下降。鉴于这些个体遭受后续脑震荡和肌肉骨骼损伤的风险增加，这些结果尤为重要。
